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Anti-CEACAM6 Antibody-FITC (3I415) is a FITC-conjugated Rabbit antibody targeting CEACAM6. Anti-CEACAM6 Antibody-FITC (3I415) can be used in FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 T | $81 | 7-10 days | |
100 T | $105 | 7-10 days |
Description | Anti-CEACAM6 Antibody-FITC (3I415) is a FITC-conjugated Rabbit antibody targeting CEACAM6. Anti-CEACAM6 Antibody-FITC (3I415) can be used in FCM. |
Alias | NCA, CEAL, CEA, CD66c, carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
Ig Type | Monoclonal Rabbit IgG |
Clone | 3I415 |
Reactivity | Human |
Verified Activity | Profile of anti-CEACAM6 (CD66c) reactivity on SK-BR3 cells analyzed by flow cytometry. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CEACAM6 / CD66c (rh CEACAM6 / CD66c; 10823-H08H; Met 1-Gly 320; NP_002474.4) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
Research Background | Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression. |
Conjucates | FITC |
Others Formats | Unconjugated |
Antibody Types Available | 2 |
Immunogen | Human cell-derived rhCEACAM6 (TMPY-00971) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Transport | Shipping with blue ice. |
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