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Anti-KIR2DL4 Antibody (1X510)

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Catalog No. TMAY-02442
Alias KIR-2DL4, KIR2DL4, KIR-103AS, KIR103AS, KIR103, KIR, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4, G9P, CD158D

Anti-KIR2DL4 Antibody (1X510) is a Mouse antibody targeting KIR2DL4. Anti-KIR2DL4 Antibody (1X510) can be used in ELISA.

Anti-KIR2DL4 Antibody (1X510)

Anti-KIR2DL4 Antibody (1X510)

😃Good
Catalog No. TMAY-02442Alias KIR-2DL4, KIR2DL4, KIR-103AS, KIR103AS, KIR103, KIR, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4, G9P, CD158D
Anti-KIR2DL4 Antibody (1X510) is a Mouse antibody targeting KIR2DL4. Anti-KIR2DL4 Antibody (1X510) can be used in ELISA.
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100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-KIR2DL4 Antibody (1X510) is a Mouse antibody targeting KIR2DL4. Anti-KIR2DL4 Antibody (1X510) can be used in ELISA.
AliasKIR-2DL4, KIR2DL4, KIR-103AS, KIR103AS, KIR103, KIR, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4, G9P, CD158D
Ig Type
Monoclonal Mouse IgG1
Clone
1X510
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human KIR2DL4 / CD158D (rh KIR2DL4 / CD158D; TMPY-03652; ADY38409.1; Met1-His242). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundKIR2DL4, also known as CD158d, is a member of the killer cell Ig-like receptor (KIR) family. KIRs are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human KIR2DL4 / CD158D Protein (TMPY-03652)
Antigen Species
Human
Biology Area
ITIM/ITAM Immunoreceptors and Related Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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