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Anti-CD166/ALCAM Antibody (5S364) (Synonyms: MEMD, CD166, activated leukocyte cell adhesion molecule)

Catalog No. TMAY-03021 Copy Product Info
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Anti-CD166/ALCAM Antibody (5S364) is a Rabbit antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody (5S364) can be used in ELISA,FCM.

Anti-CD166/ALCAM Antibody (5S364)

Copy Product Info
🥰Excellent
Catalog No. TMAY-03021
Synonyms MEMD, CD166, activated leukocyte cell adhesion molecule

Anti-CD166/ALCAM Antibody (5S364) is a Rabbit antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody (5S364) can be used in ELISA,FCM.

Anti-CD166/ALCAM Antibody
(5S364)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD166/ALCAM Antibody (5S364) is a Rabbit antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody (5S364) can be used in ELISA,FCM.
SynonymsMEMD, CD166, activated leukocyte cell adhesion molecule
Ig Type
Rabbit IgG
Clone
5S364
Reactivity
Mouse
Specificity
Mouse CD166/ALCAM
No cross-reactivity in ELISA with
Human ALCAM
Human BCAM
Human EpCAM
Human CD146
Verified Activity
Flow cytometric analysis of Mouse ALCAM(CD166) expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse ALCAM(CD166), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
Recommended Dose
ELISA: 1:5000-1:10000; FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD166 / ALCAM (rM CD166 / ALCAM; TMPY-01153; NP_033785.1; Met1-Lys527).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundActivated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-CD6) and homophilic (ALCAM-ALCAM) cell-cell interactions. ALCAM/CD6 interaction plays a role in T cell development and T cell regulation, as well as in the binding of T- and B-cells to activated leukocytes. Recently, homophilic (ALCAM-ALCAM) adhesion was shown to play important roles in tight cell-to-cell interaction and regulation of stem cell differentiation. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells involved in dynamic growth and/or migration, including neural development, branching organ development, hematopoiesis, immune response and tumor progression. And CD166 is regarded as a potential novel breast cancer indicator and therapeutic target.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
APC/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Protein: Mouse CD166 / ALCAM protein (TMPY-01153)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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