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Anti-CD166/ALCAM Antibody (5S364)
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Catalog No. TMAY-03021
Alias MEMD, CD166, activated leukocyte cell adhesion molecule
Anti-CD166/ALCAM Antibody (5S364) is a Rabbit antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody (5S364) can be used in ELISA,FCM.
Anti-CD166/ALCAM Antibody (5S364)
Anti-CD166/ALCAM Antibody (5S364)
😃Good
Catalog No. TMAY-03021Alias MEMD, CD166, activated leukocyte cell adhesion molecule
Anti-CD166/ALCAM Antibody (5S364) is a Rabbit antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody (5S364) can be used in ELISA,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-CD166/ALCAM Antibody (5S364) is a Rabbit antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody (5S364) can be used in ELISA,FCM. |
| Alias | MEMD, CD166, activated leukocyte cell adhesion molecule |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 5S364 |
| Reactivity | Mouse |
| Verified Activity | Flow cytometric analysis of Mouse ALCAM(CD166) expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse ALCAM(CD166), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | ELISA,FCM |
| Recommended Dose | ELISA: 1:5000-1:10000; FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD166 / ALCAM (rM CD166 / ALCAM; TMPY-01153; NP_033785.1; Met1-Lys527). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-CD6) and homophilic (ALCAM-ALCAM) cell-cell interactions. ALCAM/CD6 interaction plays a role in T cell development and T cell regulation, as well as in the binding of T- and B-cells to activated leukocytes. Recently, homophilic (ALCAM-ALCAM) adhesion was shown to play important roles in tight cell-to-cell interaction and regulation of stem cell differentiation. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells involved in dynamic growth and/or migration, including neural development, branching organ development, hematopoiesis, immune response and tumor progression. And CD166 is regarded as a potential novel breast cancer indicator and therapeutic target. |
| Conjucates | Unconjugated |
| Others Formats | APC/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Mouse CD166 / ALCAM protein (TMPY-01153) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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