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Anti-CD166/ALCAM Antibody (5U804) (Synonyms: MEMD, CD166, activated leukocyte cell adhesion molecule)

Name: Anti-CD166/ALCAM Antibody (5U804)
Brand: TargetMol
SKU: TMAY-00160
Rating: 4.5 (1 reviews)

Catalog No. TMAY-00160 Copy Product Info

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Anti-CD166/ALCAM Antibody (5U804) is a Mouse antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody (5U804) can be used in ELISA.

Anti-CD166/ALCAM Antibody (5U804)

Copy Product Info

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Catalog No. TMAY-00160

Synonyms MEMD, CD166, activated leukocyte cell adhesion molecule

Anti-CD166/ALCAM Antibody (5U804) is a Mouse antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody (5U804) can be used in ELISA.

Anti-CD166/ALCAM Antibody
(5U804)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 μL	$199	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-CD166/ALCAM Antibody (5U804) is a Mouse antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody (5U804) can be used in ELISA.
Synonyms	MEMD, CD166, activated leukocyte cell adhesion molecule
Ig Type	Mouse IgG1
Clone	5U804
Reactivity	Human
Specificity	Human CD166/ALCAM No cross-reactivity in ELISA with Human BCAMHuman CD146 Human CD171 Human EpCAMHuman cell lysate (293 cell line)
Application	ELISA
Recommended Dose	ELISA: 1:1000-1:2000
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD166 / ALCAM (rh CD166 / ALCAM; TMPY-01578; NP_001618.2; Met 1-Ala 526). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-CD6) and homophilic (ALCAM-ALCAM) cell-cell interactions. ALCAM/CD6 interaction plays a role in T cell development and T cell regulation, as well as in the binding of T- and B-cells to activated leukocytes. Recently, homophilic (ALCAM-ALCAM) adhesion was shown to play important roles in tight cell-to-cell interaction and regulation of stem cell differentiation. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells involved in dynamic growth and/or migration, including neural development, branching organ development, hematopoiesis, immune response and tumor progression. And CD166 is regarded as a potential novel breast cancer indicator and therapeutic target.

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Human CD166 / ALCAM Protein (TMPY-01578)
Antigen Species	Human

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

CD-166CD 166

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