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Anti-ESAM Antibody (4F225)

😃Good
Catalog No. TMAY-00424
Alias endothelial cell adhesion molecule

Anti-ESAM Antibody (4F225) is a Rabbit antibody targeting ESAM. Anti-ESAM Antibody (4F225) can be used in FCM.

Anti-ESAM Antibody (4F225)

Anti-ESAM Antibody (4F225)

😃Good
Catalog No. TMAY-00424Alias endothelial cell adhesion molecule
Anti-ESAM Antibody (4F225) is a Rabbit antibody targeting ESAM. Anti-ESAM Antibody (4F225) can be used in FCM.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Rabbit Monoclonal

Application: FCM

Reactivity: Human
Aliasendothelial cell adhesion molecule
Ig Type
Rabbit IgG
Clone
4F225
Reactivity
Human
Verified Activity
Flow cytometric analysis of human ESMA expression on HUVEC cells. Cells were stained with purified anti-Human ESMA, then a FITC-conjugated second step antibody. The histogram were derived from events with the forward and side light-scatter characteristics of intact cells.
Application
FCM
Recommended Dose
FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human Endothelial Cell Adhesion Molecule (rh Endothelial Cell Adhesion Molecule; TMPY-01312; NP_620411.2; Met1-Ala248).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundEndothelial cell-selective adhesion molecule (ESAM) is a member of JAM family of immunoglobulin superfamily and consists of one V-type and one C2-type immunoglobulin domain, as well as a hydrophobic signal sequence, a single transmembrane region, and a cytoplasmic domain. It is specifically expressed at endothelial tight junctions and on activated platelets. ESAM at endothelial tight junctions participates in the migration of neutrophils through the vessel wall, possibly by influencing endothelial cell contacts. The adaptor protein membrane-associated guanylate kinase MAGI-1 has been identified as an intracellular binding partner of ESAM. Previous studies have indicated that ESAM regulates angiogenesis in the primary tumor growth and endothelial permeability. It suggest that ESAM has a redundant functional role in physiological angiogenesis but serves a unique and essential role in pathological angiogenic processes such as tumor growth.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
APC/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Protein: Human Endothelial Cell Adhesion Molecule protein (TMPY-01312)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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