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Anti-CD166/ALCAM Antibody-FITC (3O275)
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Catalog No. TMAY-00159F
Alias MEMD, CD166, activated leukocyte cell adhesion molecule
Anti-CD166/ALCAM Antibody-FITC (3O275) is a FITC-conjugated Mouse antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody-FITC (3O275) can be used in FCM.
Anti-CD166/ALCAM Antibody-FITC (3O275)
Anti-CD166/ALCAM Antibody-FITC (3O275)
😃Good
Catalog No. TMAY-00159FAlias MEMD, CD166, activated leukocyte cell adhesion molecule
Anti-CD166/ALCAM Antibody-FITC (3O275) is a FITC-conjugated Mouse antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody-FITC (3O275) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 T | $105 | 7-10 days | |
| 100 T | $258 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD166/ALCAM Antibody-FITC (3O275) is a FITC-conjugated Mouse antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody-FITC (3O275) can be used in FCM. |
| Alias | MEMD, CD166, activated leukocyte cell adhesion molecule |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 3O275 |
| Reactivity | Human |
| Verified Activity | Profile of anti-ALCAM (CD166) reactivity on Jurkat cells analyzed by flow cytometry. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD166 / ALCAM (rh CD166 / ALCAM; TMPY-01578; NP_001618.2; Met 1-Ala 526) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-CD6) and homophilic (ALCAM-ALCAM) cell-cell interactions. ALCAM/CD6 interaction plays a role in T cell development and T cell regulation, as well as in the binding of T- and B-cells to activated leukocytes. Recently, homophilic (ALCAM-ALCAM) adhesion was shown to play important roles in tight cell-to-cell interaction and regulation of stem cell differentiation. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells involved in dynamic growth and/or migration, including neural development, branching organ development, hematopoiesis, immune response and tumor progression. And CD166 is regarded as a potential novel breast cancer indicator and therapeutic target. |
| Conjucates | FITC |
| Others Formats | Unconjugated/APC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human CD166 / ALCAM protein (TMPY-01578) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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