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Anti-INHBB/Activin B Antibody is a monoclonal antibody specifically targeting the inhibin subunit beta B (INHBB). The INHBB subunit homodimerizes to form Activin B, a member of the TGF-β superfamily involved in regulating cell proliferation, differentiation, apoptosis, and various pathological processes. By specifically binding to INHBB, this antibody blocks the interaction of Activin B with its receptors (e.g., ActRIIA/B and ALK4/7), thereby inhibiting the activation of the Smad2/3 signaling pathway. In experimental research, this antibody is frequently utilized to study liver fibrosis, muscle wasting (cachexia), and the progression mechanisms of various tumors.

| Description | Anti-INHBB/Activin B Antibody is a monoclonal antibody specifically targeting the inhibin subunit beta B (INHBB). The INHBB subunit homodimerizes to form Activin B, a member of the TGF-β superfamily involved in regulating cell proliferation, differentiation, apoptosis, and various pathological processes. By specifically binding to INHBB, this antibody blocks the interaction of Activin B with its receptors (e.g., ActRIIA/B and ALK4/7), thereby inhibiting the activation of the Smad2/3 signaling pathway. In experimental research, this antibody is frequently utilized to study liver fibrosis, muscle wasting (cachexia), and the progression mechanisms of various tumors. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | INHBB/ActivinB |
| Isotype | IgG1 |
| Storage | store at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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