Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

β-Nicotinamide mononucleotide, reduced form disodium

😃Good
Catalog No. TN11626Cas No. 108347-85-9

β-Nicotinamide mononucleotide, reduced form (NMNH) disodium is the reduced variant of β-Nicotinamide mononucleotide, with oral bioavailability. This compound significantly increases NAD+ and NADH levels while inhibiting glycolysis, the tricarboxylic acid cycle, and cell growth, mechanisms that are dependent on nicotinamide mononucleotide adenylyltransferase (NMNAT).

β-Nicotinamide mononucleotide, reduced form disodium
Other Forms of β-Nicotinamide mononucleotide, reduced form disodium:

β-Nicotinamide mononucleotide, reduced form disodium

😃Good
Catalog No. TN11626Cas No. 108347-85-9
β-Nicotinamide mononucleotide, reduced form (NMNH) disodium is the reduced variant of β-Nicotinamide mononucleotide, with oral bioavailability. This compound significantly increases NAD+ and NADH levels while inhibiting glycolysis, the tricarboxylic acid cycle, and cell growth, mechanisms that are dependent on nicotinamide mononucleotide adenylyltransferase (NMNAT).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mgInquiryInquiryInquiry
50 mgInquiryInquiryInquiry
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Resource Download

Product Introduction

Bioactivity
Description
β-Nicotinamide mononucleotide, reduced form (NMNH) disodium is the reduced variant of β-Nicotinamide mononucleotide, with oral bioavailability. This compound significantly increases NAD+ and NADH levels while inhibiting glycolysis, the tricarboxylic acid cycle, and cell growth, mechanisms that are dependent on nicotinamide mononucleotide adenylyltransferase (NMNAT).
In vitro
β-Nicotinamide mononucleotide, reduced form (100 μM; 12 h) disodium significantly increases NAD+ levels in HepG2 cells while decreasing metabolites of glycolysis and the TCA cycle. At concentrations of 250-1000 μM over 12-72 hours, β-Nicotinamide mononucleotide, reduced form disodium inhibits HepG2 cell growth and induces cell cycle arrest.
In vivo
The administration of β-Nicotinamide mononucleotide, reduced form (340 mg/kg; Intraperitoneal injection / gavage; Single time) disodium, increases NAD+ levels in the liver of male mice. Additionally, a dosage of β-Nicotinamide mononucleotide, reduced form (250 mg/kg; Intraperitoneal injection; Single time) disodium elevates NAD+ levels by 2-5 times in the liver, kidneys, brain, muscles, and whole blood of C57BL/6J mice.
Chemical Properties
Molecular Weight380.20
FormulaC11H15N2Na2O8P
Cas No.108347-85-9
SmilesO[C@H]1[C@H](N2C=C(CC=C2)C(N)=O)O[C@@H]([C@H]1O)COP([O-])([O-])=O.[Na+].[Na+]
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy β-Nicotinamide mononucleotide, reduced form disodium | purchase β-Nicotinamide mononucleotide, reduced form disodium | β-Nicotinamide mononucleotide, reduced form disodium cost | order β-Nicotinamide mononucleotide, reduced form disodium | β-Nicotinamide mononucleotide, reduced form disodium chemical structure | β-Nicotinamide mononucleotide, reduced form disodium in vivo | β-Nicotinamide mononucleotide, reduced form disodium in vitro | β-Nicotinamide mononucleotide, reduced form disodium formula | β-Nicotinamide mononucleotide, reduced form disodium molecular weight
TargetMol | Logo

Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.