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Anti-CADM3 Antibody (1Q58)
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Catalog No. TMAY-01758
Alias cell adhesion molecule 3
Anti-CADM3 Antibody (1Q58) is a Rabbit antibody targeting CADM3. Anti-CADM3 Antibody (1Q58) can be used in ELISA.
Anti-CADM3 Antibody (1Q58)
Anti-CADM3 Antibody (1Q58)
😃Good
Catalog No. TMAY-01758Alias cell adhesion molecule 3
Anti-CADM3 Antibody (1Q58) is a Rabbit antibody targeting CADM3. Anti-CADM3 Antibody (1Q58) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CADM3 Antibody (1Q58) is a Rabbit antibody targeting CADM3. Anti-CADM3 Antibody (1Q58) can be used in ELISA. |
| Alias | cell adhesion molecule 3 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 1Q58 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CADM3 (rh CADM3; TMPY-01252; NP_001120645.1; Met 1-His 330). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Cell Adhesion Molecules (CAMs) are proteins located on the cell surface involved with the binding with other cells or with the extracellular matrix (ECM) in the process called cell adhesion. These proteins are typically transmembrane receptors and are composed of three domains: an intracellular domain that interacts with the cytoskeleton, a transmembrane domain, and an extracellular domain that interacts either with other CAMs of the same kind (homophilic binding) or with other CAMs or the extracellular matrix (heterophilic binding). Cell adhesion molecule 3, also known as Immunoglobulin superfamily member 4B, CADM3, and NECL1, is a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule which has Ca(2+)-independent homo- or heterophilic cell-cell adhesion activity and plays an important role in the formation of synapses, axon bundles and myelinated axons. Isoform 1 of CADM3 is expressed mainly in adult and fetal brain. Isoform 2 of CADM3 is highly expressed in adult brain and weakly expressed in placenta. In brain, Isoform 2 is highly expressed in cerebellum. CADM3 is involved in the cell-cell adhesion. It has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, PVRL1 and PVRL3. The interaction with EPB41L1 may regulate structure or function of cell-cell junctions. CADM3 may act as a tumor suppressor in glioma and loss of it in glioma may be caused by histone deacetylation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human CADM3 protein (TMPY-01252) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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