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OMDM-6

🥰Excellent
Catalog No. T12307Cas No. 616884-67-4

OMDM-6 is a dual agonist of TRPV1(EC50 = 75 nM) and CB1 (Ki = 3.2 μM). OMDM-6 inhibits anandamide cellular uptake with a Ki of 7.0 μM.

OMDM-6

OMDM-6

🥰Excellent
Purity: 99.66%
Catalog No. T12307Cas No. 616884-67-4
OMDM-6 is a dual agonist of TRPV1(EC50 = 75 nM) and CB1 (Ki = 3.2 μM). OMDM-6 inhibits anandamide cellular uptake with a Ki of 7.0 μM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$82In StockIn Stock
5 mg$188In StockIn Stock
10 mg$277In StockIn Stock
25 mg$413In StockIn Stock
50 mg$580In StockIn Stock
100 mg$791-In Stock
200 mg$1,060-In Stock
1 mL x 10 mM (in DMSO)$208In StockIn Stock
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Expected start date of shipmentUSA Warehouse [1-2 days] Global Warehouse [5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:99.66%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
OMDM-6 is a dual agonist of TRPV1(EC50 = 75 nM) and CB1 (Ki = 3.2 μM). OMDM-6 inhibits anandamide cellular uptake with a Ki of 7.0 μM.
Targets&IC50
CB1 receptor:Ki: 3.2 μM, Anandamide cellular uptake:Ki: 7.0 μM, TRPV1:75 nM (EC50)
Chemical Properties
Molecular Weight454.64
FormulaC28H42N2O3
Cas No.616884-67-4
SmilesC(NNC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)C1=CC(OC)=C(O)C=C1
Relative Density.1.015 g/cm3 (Predicted)
Storage & Solubility Information
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (131.97 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1995 mL10.9977 mL21.9954 mL109.9771 mL
5 mM0.4399 mL2.1995 mL4.3991 mL21.9954 mL
10 mM0.2200 mL1.0998 mL2.1995 mL10.9977 mL
20 mM0.1100 mL0.5499 mL1.0998 mL5.4989 mL
50 mM0.0440 mL0.2200 mL0.4399 mL2.1995 mL
100 mM0.0220 mL0.1100 mL0.2200 mL1.0998 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TRPVChannelTRPV1TRPV ChannelTRPChannelTRP ChannelOMDM-6OMDM6OMDM 6EndogenousMetaboliteEndogenous MetaboliteCB1CannabinoidReceptorCannabinoid Receptoranandamide cellular uptake
Related Tags: buy OMDM-6 | purchase OMDM-6 | OMDM-6 cost | order OMDM-6 | OMDM-6 chemical structure | OMDM-6 formula | OMDM-6 molecular weight
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