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Anti-CRTAM Antibody (9W264)
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Catalog No. TMAY-02174
Alias cytotoxic and regulatory T cell molecule, CD355
Anti-CRTAM Antibody (9W264) is a Mouse antibody targeting CRTAM. Anti-CRTAM Antibody (9W264) can be used in FCM.
Anti-CRTAM Antibody (9W264)
Anti-CRTAM Antibody (9W264)
😃Good
Catalog No. TMAY-02174Alias cytotoxic and regulatory T cell molecule, CD355
Anti-CRTAM Antibody (9W264) is a Mouse antibody targeting CRTAM. Anti-CRTAM Antibody (9W264) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-CRTAM Antibody (9W264) is a Mouse antibody targeting CRTAM. Anti-CRTAM Antibody (9W264) can be used in FCM. |
| Alias | cytotoxic and regulatory T cell molecule, CD355 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 9W264 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CRTAM(CD355) expression on human peripheral blood lymphocytes. Human peripheral blood mononulcear cells were stimulated for 24 hours with PMA and Ionomycin, and stained with Purified anti-Human CRTAM(CD355), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CRTAM (rh CRTAM; TMPY-01674; NP_062550.2; Met1-Ser286). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Cytotoxic and regulatory T-cell molecule, also known as Class-I MHC-restricted T-cell-associated molecule and CRTAM, is a single-pass type I membrane protein which belongs to thenectin family.CRTAM contains oneIg-like C2-type (immunoglobulin-like) domain and oneIg-like V-type (immunoglobulin-like) domain. In the immune system, the expression of CRTAM is restricted to activated class-I MHC-restricted cells, including NKT and CD8 cells. It is strongly expressed in spleen, thymus, small intestine, peripheral blood leukocyte, and in purkinje neurons in cerebellum. It is expressed at much lower levels in testis, ovary, colon, lung and lymphoid tissues. CRTAM is a member of the immunoglobulin superfamily that complies with the structural characteristics of the JAM family of proteins and is phylogenetically more closely related to nectin-like proteins. It is a molecule involved in epithelial cell adhesion. CRTAM is sensitive to intermediate filament disruption and treatment of monolayers with soluble CRTAM enhances cell-cell dissociation and lowers transepithelial electrical resistance. CRTAM may also induce retention by binding to CD8+ dendritic cells (DCs) at the late stage of activation before proliferation. |
| Conjucates | Unconjugated |
| Others Formats | APC/PE |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Human CRTAM Protein (TMPY-01674) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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