Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-Tim-4/TIMD4 Antibody (3X588)
😃Good
Catalog No. TMAY-02256
Anti-Tim-4/TIMD4 Antibody (3X588) is a Rabbit antibody targeting Tim-4/TIMD4. Anti-Tim-4/TIMD4 Antibody (3X588) can be used in ELISA.
Anti-Tim-4/TIMD4 Antibody (3X588)
Anti-Tim-4/TIMD4 Antibody (3X588)
😃Good
Catalog No. TMAY-02256
Anti-Tim-4/TIMD4 Antibody (3X588) is a Rabbit antibody targeting Tim-4/TIMD4. Anti-Tim-4/TIMD4 Antibody (3X588) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
Bulk & Custom
Add to Cart
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Tim-4/TIMD4 Antibody (3X588) is a Rabbit antibody targeting Tim-4/TIMD4. Anti-Tim-4/TIMD4 Antibody (3X588) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 3X588 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human TIM4 (rh TIM4; TMPY-02124; AAH08988.1; Met1-Leu315). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | A type I transmembrane protein called TIM4 (T-cell immunoglobulin- and mucin-domain-containing molecule; also known as TIMD4), which belongs to the immunoglobulin superfamily and TIM family. TIM4 is involved in regulating T-cell proliferation and lymphotoxin signaling. It is a ligand for HAVCR1/TIMD1. Recent reports indicate that dendritic cell (DC)-derived T-cell immunoglobulin and mucin domain molecule (TIM)-4, which is expressed on dendritic cells and macrophages, plays an important role in the initiation of T(H)2 polarization. TIM4 bound apoptotic cells by recognizing phosphatidylserine via its immunoglobulin domain. The expression of TIM4 in fibroblasts enhanced their ability to engulf apoptotic cells. TIM4 is phosphatidylserine receptor for the engulfment of apoptotic cells, and may also be involved in intercellular signalling in which exosomes are involved. Modulation of TIM4 production in dendritic cells (DCs) represents a novel therapeutic approach for the treatment of peanut allergy. The interaction of TIM1/TIM4 played a critical role in sustaining the polarization status of Th2 cells in allergic rhinitis (AR) patients. Cross-linking FcgammaRI by antigen/IgG complexes increased the production of TIM4 by dendritic cells via upregulating tumor necrosis factor-alpha in DCs. Specific immunotherapy (SIT) suppresses the skewed Th2 responses via disrupting the interaction of TIM1/TIM4 in antigen-specific Th2 cells. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human TIM4 protein (TMPY-02124) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Sci Citations
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-Tim-4/TIMD4 Antibody (3X588) | purchase Anti-Tim-4/TIMD4 Antibody (3X588) | Anti-Tim-4/TIMD4 Antibody (3X588) cost | order Anti-Tim-4/TIMD4 Antibody (3X588)
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.