gr

GR 103691, a potent and selective dopamine D3 receptor antagonist (Ki: 0.4 nM), exhibits more than 100-fold selectivity for human dopamine D3 receptors over human D4 and D1 sites.

GR 113808 is a selective 5-HT4 receptor antagonist that inhibits 5-HT1B, 5-HT2A, 5-HT2C, and 5-HT3 receptors, and attenuates dopamine release.

GR148672X is an inhibitor of triacyglycerol hydrolase (TGH) (IC50: 4 nM).

GR 125487 sulfamate is a 5-HT4 receptor antagonist.

5-HT1B/1D receptor antagonist

platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist

Potent and selective tachykinin NK2 receptor antagonist

GR 94800 acetate is a potent and selective neurokinin 2(NK-2) antagonist.

GR 122222X is an inhibitor of topoisomerase II.

GR-125487 is a 5-HT4R partial agonist. It also has favorable ADME properties and good in vivo efficacy.

GR203040 inhibits cyclophosphamide-induced damage in the rat and ferret bladder. GR-203040 is a selective NK1 receptor antagonist.

GR 83895 is an antagonist of prototype fibrinogen receptor.

GR 128107 is an antagonist of melatonin receptor.

GR-55562 dihydrobromide is a antagonist of 5-HT1B/5-HT1D serotonin receptor.

GR-112000 is a peptide-based tachykinin NK2 receptor antagonist.

GR-127935 is a potent and selective 5-HT1B/1D receptor antagonist.

GR-92549 is an HMG-CoA reductase inhibitor.

GR-36246 is a Thromboxane A2-receptor blocker.

GR-95030X is a a novel HMG-CoA reductase inhibitor.

GR-71251 is a Tachykinin receptor antagonist.

GR 125743 is a novel antagonist of 5-HT1B/1D receptor.

GR103545 is a selective agonist of the κ-opioid receptor, which is a radiotracer that can be used as in vivo imaging.

Potent and selective tachykinin NK1 receptor agonist (EC50 = 2 nM in guinea pig vas deferens).

Potent neuropeptide Y (NPY) Y1 receptor antagonist (pA2 = 10 and 10.5 at rY1 and hY1, receptors respectively). Also a potent and selective NPY Y4 receptor agonist (pEC50 values are 6.0, 8.6 and 6.1 for rY2, hY4 and rY5 receptors respectively). Suppresses