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Anti-Midkine Antibody (9X800)
😃Good
Catalog No. TMAY-00520
Alias NEGF2, MK, midkine (neurite growth-promoting factor 2), ARAP
Anti-Midkine Antibody (9X800) is a Mouse antibody targeting Midkine. Anti-Midkine Antibody (9X800) can be used in ELISA.
Anti-Midkine Antibody (9X800)
Anti-Midkine Antibody (9X800)
😃Good
Catalog No. TMAY-00520Alias NEGF2, MK, midkine (neurite growth-promoting factor 2), ARAP
Anti-Midkine Antibody (9X800) is a Mouse antibody targeting Midkine. Anti-Midkine Antibody (9X800) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Midkine Antibody (9X800) is a Mouse antibody targeting Midkine. Anti-Midkine Antibody (9X800) can be used in ELISA. |
| Alias | NEGF2, MK, midkine (neurite growth-promoting factor 2), ARAP |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 9X800 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Midkine (rh Midkine; TMPY-02172; P21741; Met1-Asp143). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Midkine (MK or MDK) also known as neurite growth-promoting factor 2 (NEGF2) is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin. Midkine is a retinoic acid-responsive, heparin-binding growth factor expressed in various cell types during embryogenesis. It promotes angiogenesis, cell growth, and cell migration. Midkine is also expressed in several carcinomas, suggesting that it may play a role in tumorigenesis, perhaps through its effects on angiogenesis. Midkine binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase and the induction of cell proliferation. Midkine is involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development. Midkine exhibited increased expression in the breast carcinomas but showed much lower expression in the normal breast tissue. Thus, it can be used as a breast carcinomas marker. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human Midkine Protein (TMPY-02172) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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