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Anti-GRO beta/CXCL2 Antibody (9H881)
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Catalog No. TMAY-03073
Anti-GRO beta/CXCL2 Antibody (9H881) is a Rabbit antibody targeting GRO beta/CXCL2. Anti-GRO beta/CXCL2 Antibody (9H881) can be used in ELISA.
Anti-GRO beta/CXCL2 Antibody (9H881)
Anti-GRO beta/CXCL2 Antibody (9H881)
😃Good
Catalog No. TMAY-03073
Anti-GRO beta/CXCL2 Antibody (9H881) is a Rabbit antibody targeting GRO beta/CXCL2. Anti-GRO beta/CXCL2 Antibody (9H881) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-GRO beta/CXCL2 Antibody (9H881) is a Rabbit antibody targeting GRO beta/CXCL2. Anti-GRO beta/CXCL2 Antibody (9H881) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 9H881 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CXCL2/MIP-2 (rM CXCL2/MIP-2; TMPY-02064; P10889-1; Ala28-Asn100). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Chemokine (C-X-C motif) ligand 2 (CXCL2), also called macrophage inflammatory protein 2 (MIP-2), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2), is a small cytokine belonging to the CXC chemokine family. CXCL2/MIP-2 is selectively up-regulated in tolerance-conferring APCs and serves to recruit NKT cells to the splenic marginal zone, where they form clusters with APCs and T cells. In the absence of the high-affinity receptor for CXCL2/MIP-2 or in the presence of a blocking Ab to CXCL2/MIP-2, peripheral tolerance is prevented, and Ag-specific T regulatory cells are not generated. CXCL2/MIP-2 is selectively up-regulated in tolerance-conferring APCs and serves to recruit NKT cells to the splenic marginal zone, where they form clusters with APCs and T cells. In the absence of the high-affinity receptor for MIP-2 (as in CXCR2-deficient mice) or in the presence of a blocking Ab to MIP-2, peripheral tolerance is prevented, and Ag-specific T regulatory cells are not generated. Understanding the regulation of lymphocyte traffic during tolerance induction may lead to novel therapies for autoimmunity, graft acceptance, and tumor rejection. Several studies have implicated the CXCL2 chemokine as a mediator in the development of sepsis. CXCL2/MIP-2 also plays a major role in mediating the neutrophilic inflammatory response of the rodent lung to particles such as quartz, crocidolite asbestos, as well as high doses of other relative innocuous dusts such as titanium dioxide. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse CXCL2/MIP-2 Protein (TMPY-02064) |
| Antigen Species | Mouse |
| Biology Area | Neuroinflammation |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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