Anti-EGF Antibody (9E161) (Synonyms: epidermal growth factor)

Name: Anti-EGF Antibody (9E161)
Brand: TargetMol
SKU: TMAY-03835
Rating: 4.5 (1 reviews)

Catalog No. TMAY-03835 Copy Product Info

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Anti-EGF Antibody (9E161) is a Mouse antibody targeting EGF. Anti-EGF Antibody (9E161) can be used in ELISA.

Anti-EGF Antibody (9E161)

Copy Product Info

🥰Excellent

Catalog No. TMAY-03835

Synonyms epidermal growth factor

Anti-EGF Antibody (9E161) is a Mouse antibody targeting EGF. Anti-EGF Antibody (9E161) can be used in ELISA.

Anti-EGF Antibody
(9E161)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 μL	$198	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-EGF Antibody (9E161) is a Mouse antibody targeting EGF. Anti-EGF Antibody (9E161) can be used in ELISA.
Synonyms	epidermal growth factor
Ig Type	Mouse IgG1
Clone	9E161
Reactivity	Rat
Specificity	Rat EGF
Application	ELISA
Recommended Dose	ELISA: 1:1000-1:2000
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat Epidermal Growth Factor / EGF (rR Epidermal Growth Factor / EGF; TMPY-04220; NP_036974.1; Asn974-Arg1026). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats. Human EGF is a 6045-Da protein with 53 amino acid residues and three intramolecular disulfide bonds. As a low-molecular-weight polypeptide, EGF was first purified from the mouse submandibular gland, but since then it was found in many human tissues including submandibular gland, parotid gland. It can also be found in human platelets, macrophages, urine, saliva, milk, and plasma. EGF is a growth factor that stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. It results in cellular proliferation, differentiation, and survival. Salivary EGF, which seems also regulated by dietary inorganic iodine, also plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity. EGF acts by binding with high affinity to epidermal growth factor receptor on the cell surface and stimulating the intrinsic protein-tyrosine kinase activity of the receptor. The tyrosine kinase activity, in turn, initiates a signal transduction cascade that results in a variety of biochemical changes within the cell - a rise in intracellular calcium levels, increased glycolysis and protein synthesis, and increases in the expression of certain genes including the gene for EGFR - that ultimately lead to DNA synthesis and cell proliferation.

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Rat Epidermal Growth Factor / EGF Protein (TMPY-04220)
Antigen Species	Rat

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.