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Anti-CD16/FCGR3 Antibody (1A938)

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Catalog No. TMAY-00742
Alias Fc receptor, IgG, low affinity III, CD16

Anti-CD16/FCGR3 Antibody (1A938) is a Mouse antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody (1A938) can be used in FCM.

Anti-CD16/FCGR3 Antibody (1A938)

Anti-CD16/FCGR3 Antibody (1A938)

😃Good
Catalog No. TMAY-00742Alias Fc receptor, IgG, low affinity III, CD16
Anti-CD16/FCGR3 Antibody (1A938) is a Mouse antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody (1A938) can be used in FCM.
Pack SizePriceAvailabilityQuantity
20 μL$69 7-10 days
100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-CD16/FCGR3 Antibody (1A938) is a Mouse antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody (1A938) can be used in FCM.
AliasFc receptor, IgG, low affinity III, CD16
Ig Type
Monoclonal Mouse IgG1
Clone
1A938
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human CD16 expression on human whole blood lymphocytes. Cells were stained with purified anti-Human CD16, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
Application
FCM
Recommended Dose
FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD16a/Fc gamma RIIIa (rh CD16a/Fc gamma RIIIa; TMPY-00763; P08637-1; Met1-Gln208,176F). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundFc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
APC/PerCP/FITC/PE
Antibody Types Available
5
Antigen Details
Immunogen
Recombinant Human CD16a/Fc gamma RIIIa Protein (TMPY-00763)
Antigen Species
Human
Biology Area
Fc Receptors
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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