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Anti-GRM2 Monoclonal Antibody (9X361)
(Synonyms: MGLUR2, mGlu2, GPRC1B, GLUR2) Copy Product Info
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Synonyms: MGLUR2, mGlu2, GPRC1B, GLUR2
Catalog No. TMAT-1304 Copy Product Info
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Anti-GRM2 Monoclonal Antibody (9X361) is a Mouse antibody targeting GRM2. Anti-GRM2 Monoclonal Antibody (9X361) can be used in WB,FCM.
Anti-GRM2 Monoclonal Antibody
(9X361)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-GRM2 Monoclonal Antibody (9X361) is a Mouse antibody targeting GRM2. Anti-GRM2 Monoclonal Antibody (9X361) can be used in WB,FCM. |
| Synonyms | MGLUR2, mGlu2, GPRC1B, GLUR2 |
| Ig Type | IgG1 |
| Clone | 9X361 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human GRM2 (AA: extra 414-558) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | GRM2 |
| Gene ID | |
| Protein Name | Metabotropic glutamate receptor 2 |
| Uniprot ID |
| Molecular Weight | Theoretical: 95.6 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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