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Anti-CSF3R/G-CSFR Antibody (4I21)
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Catalog No. TMAY-00481
Alias GCSFR, G-CSF R, CSF3R, colony stimulating factor 3 receptor (granulocyte), CD114
Anti-CSF3R/G-CSFR Antibody (4I21) is a Mouse antibody targeting CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Antibody (4I21) can be used in ELISA(Cap),ICC/IF.
Anti-CSF3R/G-CSFR Antibody (4I21)
Anti-CSF3R/G-CSFR Antibody (4I21)
😃Good
Catalog No. TMAY-00481Alias GCSFR, G-CSF R, CSF3R, colony stimulating factor 3 receptor (granulocyte), CD114
Anti-CSF3R/G-CSFR Antibody (4I21) is a Mouse antibody targeting CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Antibody (4I21) can be used in ELISA(Cap),ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $69 | 7-10 days | |
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA(Cap), ICC/IF Reactivity: Human |
| Alias | GCSFR, G-CSF R, CSF3R, colony stimulating factor 3 receptor (granulocyte), CD114 |
| Ig Type | Mouse IgG1 |
| Clone | 4I21 |
| Reactivity | Human |
| Verified Activity | Confocal immunofluorescence analysis of Human GCSFR in MCF7 cells. Cells were fixed with 4% PFA, permeabilzed with 1% Triton X-100 in PBS, blocked with 10% serum, and incubated with Mouse anti-Human GCSFR monoclonal antibody (1:60). Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-mouse IgG secondary antibody, countstained with Alexa Fluor® 546-conjugated phallotoxins (red) and DAPI (blue). Positive staining was localized to cytoplasm and cytomembrane. |
| Application | ELISA(Cap),ICC/IF |
| Recommended Dose | ICC-IF: 1:20-1:100; ELISA(Cap): 1:250-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human G-CSFR / CD114 (rh G-CSFR / CD114; NP_000751.1Met1-Pro621). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Granulocyte Colony Stimulating Factor Receptor (G-CSFR), also known as CD114, which belongs to the cytokine receptor superfamily, is a cell surface receptor for colony stimulating factor 3 (CSF3). It is a critical regulator of granulopoiesis. This type I membrane protein has a composite structure consisting of an immunoglobulin(Ig)-like domain, a cytokine receptor-homologous (CRH) domain and three fibronectin type III (FNIII) domains in the extracellular region. Mutations in the G-CSF receptor leading to carboxy-terminal truncation transduce hyperproliferative growth responses, and are implicated in the pathological progression of severe congenital neutropenia (SCN) to acute myelogenous leukemia (AML). Additionally, autocrine/paracrine stimulation of G-CSFR may be important in the biology of solid tumors, including metastasis. |
| Conjucates | Unconjugated |
| Others Formats | APC/PE |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Protein: Human G-CSFR / CD114 protein |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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