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Synonyms: SRC2, p58c-fgr, p55c-fgr, c-src2, c-fgr
Anti-FGR Monoclonal Antibody
(8L816)

| Description | Anti-FGR Monoclonal Antibody (8L816) is a Mouse antibody targeting FGR. Anti-FGR Monoclonal Antibody (8L816) can be used in WB,IHC. |
| Synonyms | SRC2, p58c-fgr, p55c-fgr, c-src2, c-fgr |
| Ig Type | IgG1 |
| Clone | 8L816 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | FGR: Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, also known as SRC2; c-fgr; c-src2; FLJ43153; MGC75096; p55c-fgr; p58c-fgr. It is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human FGR expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | FGR |
| Gene ID | |
| Protein Name | Tyrosine-protein kinase Fgr |
| Uniprot ID |
| Molecular Weight | Theoretical: 56 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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