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Anti-TGFBR3 Antibody (1I111)

😃Good
Catalog No. TMAY-03351
Alias βglycan, transforming growth factor, β receptor III, transforming growth factor, beta receptor III, BGCAN, betaglycan

Anti-TGFBR3 Antibody (1I111) is a Rabbit antibody targeting TGFBR3. Anti-TGFBR3 Antibody (1I111) can be used in ELISA.

Anti-TGFBR3 Antibody (1I111)

Anti-TGFBR3 Antibody (1I111)

😃Good
Catalog No. TMAY-03351Alias βglycan, transforming growth factor, β receptor III, transforming growth factor, beta receptor III, BGCAN, betaglycan
Anti-TGFBR3 Antibody (1I111) is a Rabbit antibody targeting TGFBR3. Anti-TGFBR3 Antibody (1I111) can be used in ELISA.
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100 μL$270 7-10 days
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Product Introduction

Bioactivity
Description
Anti-TGFBR3 Antibody (1I111) is a Rabbit antibody targeting TGFBR3. Anti-TGFBR3 Antibody (1I111) can be used in ELISA.
Aliasβglycan, transforming growth factor, β receptor III, transforming growth factor, beta receptor III, BGCAN, betaglycan
Ig Type
Monoclonal Rabbit IgG
Clone
1I111
Reactivity
Mouse
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse TGFBR3 (rM TGFBR3; TMPY-02224; NP_035708.2; Met1-Arg399).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundBetaglycan also known as transforming growth factor beta receptor III (TGFBR3), is a cell-surface chondroitin sulfate / heparan sulfate proteoglycan. TGFBR3 is a transforming growth factor (TGF)-beta type III receptor. This receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. TGFBR3 is the TGF-β component most commonly downregulated among localized human prostate cancer studies. TGFBR3 knockdown led to focus formation and enhanced expression of CD133, a marker found on prostate cancer stem cells. TGFBR3 is an accessory receptor that binds to and modulates the activities of both transforming growth factor-beta (TGFβ) and inhibin, two members of the TGFβ superfamily of growth factors that regulate many aspects of reproductive biology. TGFBR3 is known to be expressed in adult testis and ovary, but little is known about this receptor during gonadogenesis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse TGFBR3 protein (TMPY-02224)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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