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Anti-CD16/FCGR3 Antibody (6W413)

(Synonyms: Fc receptor, IgG, low affinity III, CD16) Copy Product Info
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Synonyms: Fc receptor, IgG, low affinity III, CD16

Catalog No. TMAY-03235 Copy Product Info
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Anti-CD16/FCGR3 Antibody (6W413) is a Rabbit antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody (6W413) can be used in ELISA,IP,WB.
Anti-CD16/FCGR3 Antibody
(6W413)
Pack SizePriceUSA StockGlobal StockQuantity
20 μL$927-10 days7-10 days
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD16/FCGR3 Antibody (6W413) is a Rabbit antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody (6W413) can be used in ELISA,IP,WB.
SynonymsFc receptor, IgG, low affinity III, CD16
Ig Type
Rabbit IgG
Clone
6W413
Reactivity
Mouse
Specificity
Mouse CD16/FCGR3/Fc gamma RIII
Has cross-reactivity in ELISA with
Human CD64
No cross-reactivity in ELISA with
Human CD32a
Human CD32b
Human CD16a
Human CD16b
Cynomolgus FCGR3
Application
Recommended Dose
WB: 1:500-1:2000; ELISA: 1:5000-1:10000; IP: 0.5-2 μL/mg of lysate
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD16 / FCGR3 (rM CD16 / FCGR3; TMPY-01834; P08508-1; Met 1-Thr 215).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundFc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Mouse CD16 / FCGR3 protein (TMPY-01834)
Antigen Species
Mouse
Biology Area
Fc Receptors
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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