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Anti-GRM8 Monoclonal Antibody (8D464)
(Synonyms: MGLUR8, mGlu8, GPRC1H, GLUR8) Copy Product Info
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Synonyms: MGLUR8, mGlu8, GPRC1H, GLUR8
Catalog No. TMAT-0515 Copy Product Info
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Anti-GRM8 Monoclonal Antibody (8D464) is a Mouse antibody targeting GRM8. Anti-GRM8 Monoclonal Antibody (8D464) can be used in WB,FCM.
Anti-GRM8 Monoclonal Antibody
(8D464)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-GRM8 Monoclonal Antibody (8D464) is a Mouse antibody targeting GRM8. Anti-GRM8 Monoclonal Antibody (8D464) can be used in WB,FCM. |
| Synonyms | MGLUR8, mGlu8, GPRC1H, GLUR8 |
| Ig Type | IgG1 |
| Clone | 8D464 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human GRM8 (AA: extra 440-583) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | GRM8 |
| Gene ID | |
| Protein Name | Metabotropic glutamate receptor 8 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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