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Anti-G-CSF Antibody (3B809) (Synonyms: MGI-IG, G-CSF, Csfg, colony stimulating factor 3 (granulocyte))
Catalog No. TMAY-00048 Copy Product Info
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Anti-G-CSF Antibody (3B809) is a Mouse antibody targeting G-CSF. Anti-G-CSF Antibody (3B809) can be used in ELISA,WB.
Anti-G-CSF Antibody (3B809)
Copy Product Info🥰Excellent
Catalog No. TMAY-00048
Synonyms MGI-IG, G-CSF, Csfg, colony stimulating factor 3 (granulocyte)
Anti-G-CSF Antibody (3B809) is a Mouse antibody targeting G-CSF. Anti-G-CSF Antibody (3B809) can be used in ELISA,WB.
Anti-G-CSF Antibody
(3B809)
(3B809)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $199 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Bioactivity
Related Conjugates and Formulations
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| Description | Anti-G-CSF Antibody (3B809) is a Mouse antibody targeting G-CSF. Anti-G-CSF Antibody (3B809) can be used in ELISA,WB. |
| Synonyms | MGI-IG, G-CSF, Csfg, colony stimulating factor 3 (granulocyte) |
| Ig Type | Mouse IgG2a |
| Clone | 3B809 |
| Reactivity | Human |
| Specificity | Human G-CSF |
| Verified Activity | Anti-G-CSF mouse monoclonal antibody at 1:500 dilution. -Lane A: NCI-H460 Whole Cell Lysate. -Lane A: 293T Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Mouse IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:22 kDa. -Observed band size:25 kDa |
| Application | |
| Recommended Dose | WB: 1:500-1:2000; ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human G-CSF (rh interferon-alpha/G-CSF; NP_757373.1; Met1-Pro204). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial cells. G-CSF binding to its receptor G-CSF-R which belongs to the cytokine receptor type I family depends on the interaction of alpha-helical motifs of the former and two fibronectin type III as well as an immunoglobulin-like domain of the latter. Recent animal studies have also revealed that G-CSF activates multiple signaling pathways, such as Akt and also the Janus family kinase-2 and signal transducer and activation of transcription-3 (Jak2-STAT3) pathway, thereby promoting survival, proliferation, differentiation and mobilisation of haematopoietic stem and progenitor cells. G-CSF is a cytokine that have been demonstrated to improve cardiac function and perfusion in myocardial infarction. And it was initially evaluated as a stem cell mobilizer and erythropoietin as a cytoprotective agent. G-CSF prevents left ventricular remodeling after myocardial infarction by decreasing cardiomyocyte death and by increasing the number of blood vessels, suggesting the importance of direct actions of G-CSF on the myocardium rather than through mobilization and differentiation of stem cells. Accordingly, recombinant human (rh)G-CSF has been extensively used in clinical haematology and oncology to enable bone marrow transplantation or to treat chemotherapy-associated neutropenia. In preclinical study, G-CSF improved cardiac function and perfusion by angiomyogenesis and protection of cardiomyocytes in myocardial infarction.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human G-CSF Protein |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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