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Anti-CD16/FCGR3 Antibody (4O520)
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Catalog No. TMAY-03234
Alias Fc receptor, IgG, low affinity III, CD16
Anti-CD16/FCGR3 Antibody (4O520) is a Rabbit antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody (4O520) can be used in FCM.
Anti-CD16/FCGR3 Antibody (4O520)
Anti-CD16/FCGR3 Antibody (4O520)
😃Good
Catalog No. TMAY-03234Alias Fc receptor, IgG, low affinity III, CD16
Anti-CD16/FCGR3 Antibody (4O520) is a Rabbit antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody (4O520) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD16/FCGR3 Antibody (4O520) is a Rabbit antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody (4O520) can be used in FCM. |
| Alias | Fc receptor, IgG, low affinity III, CD16 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4O520 |
| Reactivity | Mouse |
| Verified Activity | Flow cytometric analysis of Mouse FCGR3(CD16) expression on mouse splenocytes. BABL/c splenocytes were stained with purified anti-Mouse FCGR3(CD16), then a FITC-conjugated second step antibody. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD16 / FCGR3 (rm CD16 / FCGR3; TMPY-01834; P08508-1; Met1-Thr215). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes. |
| Conjucates | Unconjugated |
| Others Formats | APC/PerCP/FITC/PE |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Mouse CD16 / FCGR3 protein (TMPY-01834) |
| Antigen Species | Mouse |
| Biology Area | Fc Receptors |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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