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Anti-GRM3 Monoclonal Antibody (7Y944)
(Synonyms: MGLUR3, mGlu3, GPRC1C, GLUR3) Copy Product Info
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Synonyms: MGLUR3, mGlu3, GPRC1C, GLUR3
Catalog No. TMAT-1312 Copy Product Info
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Anti-GRM3 Monoclonal Antibody (7Y944) is a Mouse antibody targeting GRM3. Anti-GRM3 Monoclonal Antibody (7Y944) can be used in IHC,IF,FCM.
Anti-GRM3 Monoclonal Antibody
(7Y944)
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Product Introduction
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Related Conjugates and Formulations
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| Description | Anti-GRM3 Monoclonal Antibody (7Y944) is a Mouse antibody targeting GRM3. Anti-GRM3 Monoclonal Antibody (7Y944) can be used in IHC,IF,FCM. |
| Synonyms | MGLUR3, mGlu3, GPRC1C, GLUR3 |
| Ig Type | IgG2a |
| Clone | 7Y944 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human GRM3 (AA: extra 433-576) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | GRM3 |
| Gene ID | |
| Protein Name | Metabotropic glutamate receptor 3 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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