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7-oxo-Mogroside V

Name: 7-oxo-Mogroside V
Brand: TargetMol
SKU: TN13044
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. TN13044 Copy Product Info

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7-oxo-Mogroside V is a cucurbitane-type triterpenoid saponin isolated from Siraitia grosvenorii fruits. It inhibits TPA-induced activation of EBV-EA (Epstein–Barr virus early antigen) and shows weak inhibitory effects on the activation of the nitric oxide donor NOR 1, with potential applications in oncology research.

7-oxo-Mogroside V

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Catalog No. TN13044

Cas No. 942612-72-8

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Pack Size	Price	USA Stock	Global Stock
1 mg	$195	-	In Stock
5 mg	$483	-	In Stock
10 mg	$691	-	In Stock
25 mg	$1,080	-	In Stock
50 mg	$1,490	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description

In vitro

Methods: Raji cells were co-treated with 7-oxo-Mogroside V and TPA at different molar ratios to detect the activation of EBV-EA; Chang hepatocytes were treated with 350 nmol 7-oxo-Mogroside V to detect its inhibitory effect on NOR 1 activation.
Results:
1 7-oxo-Mogroside V (10–1000 mol ratio/32 pmol TPA) could inhibit TPA-induced EBV-EA activation in Raji cells, with an IC₅₀ of 400 mol ratio/32 pmol TPA.
2 7-oxo-Mogroside V (350 nmol) only exhibited a weak inhibitory effect on the activation of NOR 1 in Chang hepatocytes, with an inhibition rate of 1.4 [1].

Chemical Properties

Molecular Weight	1301.42
Formula	C₆₀H₁₀₀O₃₀
Cas No.	942612-72-8
Smiles	C[C@]12[C@]([C@@]3(C)[C@](C)(C[C@H]1O)[C@@]([C@@H](CC[C@@H](O[C@H]4[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)O4)[C@@](C)(C)O)C)(CC3)[H])(C(=O)C=C7[C@]2(CC[C@H](O[C@@H]8O[C@H](CO[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@@H](O)[C@H](O)[C@H]8O)C7(C)C)[H])[H]

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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