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Anti-CSF3R/G-CSFR Antibody (4H46)
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Catalog No. TMAY-00480
Alias GCSFR, G-CSF R, CSF3R, colony stimulating factor 3 receptor (granulocyte), CD114
Anti-CSF3R/G-CSFR Antibody (4H46) is a Mouse antibody targeting CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Antibody (4H46) can be used in ELISA,ELISA(Det).
Anti-CSF3R/G-CSFR Antibody (4H46)
Anti-CSF3R/G-CSFR Antibody (4H46)
😃Good
Catalog No. TMAY-00480Alias GCSFR, G-CSF R, CSF3R, colony stimulating factor 3 receptor (granulocyte), CD114
Anti-CSF3R/G-CSFR Antibody (4H46) is a Mouse antibody targeting CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Antibody (4H46) can be used in ELISA,ELISA(Det).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $68 | 7-10 days | |
| 100 μL | $198 | 7-10 days |
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Chemical Properties
| Description | Anti-CSF3R/G-CSFR Antibody (4H46) is a Mouse antibody targeting CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Antibody (4H46) can be used in ELISA,ELISA(Det). |
| Synonyms | GCSFR, G-CSF R, CSF3R, colony stimulating factor 3 receptor (granulocyte), CD114 |
| Ig Type | Mouse IgG1 |
| Clone | 4H46 |
| Reactivity | Human |
| Specificity | Human CSF3R/G-CSFR |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000; ELISA(Det): 1:1000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human G-CSFR extracellular domain (rhG-CSFR; Catalog #10218-HCCH; Met1-Pro621; NP_000751.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Granulocyte Colony Stimulating Factor Receptor (G-CSFR), also known as CD114, which belongs to the cytokine receptor superfamily, is a cell surface receptor for colony stimulating factor 3 (CSF3). It is a critical regulator of granulopoiesis. This type I membrane protein has a composite structure consisting of an immunoglobulin(Ig)-like domain, a cytokine receptor-homologous (CRH) domain and three fibronectin type III (FNIII) domains in the extracellular region. Mutations in the G-CSF receptor leading to carboxy-terminal truncation transduce hyperproliferative growth responses, and are implicated in the pathological progression of severe congenital neutropenia (SCN) to acute myelogenous leukemia (AML). Additionally, autocrine/paracrine stimulation of G-CSFR may be important in the biology of solid tumors, including metastasis. |
| Conjucates | Unconjugated |
| Immunogen | Human cell-derived rhG-CSFR extracellular domain |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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