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Anti-CSF3R/G-CSFR Antibody (4H46)

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Catalog No. TMAY-00480
Alias GCSFR, G-CSF R, CSF3R, colony stimulating factor 3 receptor (granulocyte), CD114

Anti-CSF3R/G-CSFR Antibody (4H46) is a Mouse antibody targeting CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Antibody (4H46) can be used in ELISA,ELISA(Det).

Anti-CSF3R/G-CSFR Antibody (4H46)

Anti-CSF3R/G-CSFR Antibody (4H46)

😃Good
Catalog No. TMAY-00480Alias GCSFR, G-CSF R, CSF3R, colony stimulating factor 3 receptor (granulocyte), CD114
Anti-CSF3R/G-CSFR Antibody (4H46) is a Mouse antibody targeting CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Antibody (4H46) can be used in ELISA,ELISA(Det).
Pack SizePriceAvailabilityQuantity
20 μL$68 7-10 days
100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-CSF3R/G-CSFR Antibody (4H46) is a Mouse antibody targeting CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Antibody (4H46) can be used in ELISA,ELISA(Det).
AliasGCSFR, G-CSF R, CSF3R, colony stimulating factor 3 receptor (granulocyte), CD114
Ig Type
Monoclonal Mouse IgG1
Clone
4H46
Reactivity
Human
Application
ELISA,ELISA(Det)
Recommended Dose
ELISA: 1:1000-1:2000; ELISA(Det): 1:1000-1:10000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human G-CSFR extracellular domain (rhG-CSFR; Catalog #10218-HCCH; Met1-Pro621; NP_000751.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundGranulocyte Colony Stimulating Factor Receptor (G-CSFR), also known as CD114, which belongs to the cytokine receptor superfamily, is a cell surface receptor for colony stimulating factor 3 (CSF3). It is a critical regulator of granulopoiesis. This type I membrane protein has a composite structure consisting of an immunoglobulin(Ig)-like domain, a cytokine receptor-homologous (CRH) domain and three fibronectin type III (FNIII) domains in the extracellular region. Mutations in the G-CSF receptor leading to carboxy-terminal truncation transduce hyperproliferative growth responses, and are implicated in the pathological progression of severe congenital neutropenia (SCN) to acute myelogenous leukemia (AML). Additionally, autocrine/paracrine stimulation of G-CSFR may be important in the biology of solid tumors, including metastasis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Human cell-derived rhG-CSFR extracellular domain
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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