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Anti-FGF-19 Antibody (2F284)
😃Good
Catalog No. TMAY-02289
Alias fibroblast growth factor 19, FGF19
Anti-FGF-19 Antibody (2F284) is a Rabbit antibody targeting FGF-19. Anti-FGF-19 Antibody (2F284) can be used in ELISA.
Anti-FGF-19 Antibody (2F284)
Anti-FGF-19 Antibody (2F284)
😃Good
Catalog No. TMAY-02289Alias fibroblast growth factor 19, FGF19
Anti-FGF-19 Antibody (2F284) is a Rabbit antibody targeting FGF-19. Anti-FGF-19 Antibody (2F284) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | fibroblast growth factor 19, FGF19 |
| Ig Type | Rabbit IgG |
| Clone | 2F284 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human FGF19 / FGF-19 (rh FGF19 / FGF-19; TMPY-02907; O95750-1; Phe27-Lys216). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF19 interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglycans that function as coreceptors. It interacts with KL and KLB directly. However, it interacts with FGFR4 in the presence of heparin, KL or KLB. FGF19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. It also stimulates glucose uptake in adipocytes. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human FGF19 / FGF-19 protein (TMPY-02907) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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