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GSK9027

Name: GSK9027
Brand: TargetMol
SKU: T22818
Price: 32 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T22818Cas No. 1229096-88-1

Alias GSK-9027, GSK 9027, GR agonist 23a

GSK9027 (GR agonist 23a) is a nonsteroidal glucocorticoid receptor (GR) agonist.GSK9027 is a partial agonist on the 2×GRE reporter gene compared to dexamethasone and is less active than dexamethasone activity.

GSK9027

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Purity: 99.31%

Catalog No. T22818Alias GSK-9027, GSK 9027, GR agonist 23aCas No. 1229096-88-1

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$32	-	In Stock
5 mg	$54	-	In Stock
10 mg	$90	-	In Stock
25 mg	$188	-	In Stock
50 mg	$272	-	In Stock
100 mg	$373	-	In Stock
200 mg	$510	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.31%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	GSK9027 (GR agonist 23a) is a nonsteroidal glucocorticoid receptor (GR) agonist.GSK9027 is a partial agonist on the 2×GRE reporter gene compared to dexamethasone and is less active than dexamethasone activity.
Synonyms	GSK-9027, GSK 9027, GR agonist 23a

Chemical Properties

Molecular Weight	525.52
Formula	C₂₇H₁₉F₄N₃O₂S
Cas No.	1229096-88-1
Smiles	FC1=CC=C(N2C=3C(=CC(=CC3)C4=C(C(F)(F)F)C=C(NS(CC5=CC=CC=C5)(=O)=O)C=C4)C=N2)C=C1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (114.17 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9029 mL	9.5144 mL	19.0288 mL	95.1439 mL
5 mM	0.3806 mL	1.9029 mL	3.8058 mL	19.0288 mL
10 mM	0.1903 mL	0.9514 mL	1.9029 mL	9.5144 mL
20 mM	0.0951 mL	0.4757 mL	0.9514 mL	4.7572 mL
50 mM	0.0381 mL	0.1903 mL	0.3806 mL	1.9029 mL
100 mM	0.0190 mL	0.0951 mL	0.1903 mL	0.9514 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc