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(Iso)-Samixogrel

🥰Excellent
Catalog No. T68136Cas No. 133276-52-5

(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.

(Iso)-Samixogrel

(Iso)-Samixogrel

🥰Excellent
Purity: 98.80%
Catalog No. T68136Cas No. 133276-52-5
(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$52In StockIn Stock
5 mg$126In StockIn Stock
10 mg$186In StockIn Stock
25 mg$352In StockIn Stock
50 mg$486In StockIn Stock
100 mg$672In StockIn Stock
200 mg$888-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:98.80%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.
Chemical Properties
Molecular Weight484.99
FormulaC25H25ClN2O4S
Cas No.133276-52-5
SmilesC(=CCCCC(O)=O)(C1=CC=C(CCNS(=O)(=O)C2=CC=C(Cl)C=C2)C=C1)C=3C=CC=NC3
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (103.09 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0619 mL10.3095 mL20.6190 mL103.0949 mL
5 mM0.4124 mL2.0619 mL4.1238 mL20.6190 mL
10 mM0.2062 mL1.0309 mL2.0619 mL10.3095 mL
20 mM0.1031 mL0.5155 mL1.0309 mL5.1547 mL
50 mM0.0412 mL0.2062 mL0.4124 mL2.0619 mL
100 mM0.0206 mL0.1031 mL0.2062 mL1.0309 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

COX-2CarbonicAnhydraseCarbonic AnhydraseCarbonic anhydrase
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