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Anti-Secretogranin II Antibody (1S984)

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Catalog No. TMAY-02584
Alias SN, SgII, secretogranin II, EM66, CHGC

Anti-Secretogranin II Antibody (1S984) is a Mouse antibody targeting Secretogranin II. Anti-Secretogranin II Antibody (1S984) can be used in ELISA.

Anti-Secretogranin II Antibody (1S984)

Anti-Secretogranin II Antibody (1S984)

😃Good
Catalog No. TMAY-02584Alias SN, SgII, secretogranin II, EM66, CHGC
Anti-Secretogranin II Antibody (1S984) is a Mouse antibody targeting Secretogranin II. Anti-Secretogranin II Antibody (1S984) can be used in ELISA.
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100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Secretogranin II Antibody (1S984) is a Mouse antibody targeting Secretogranin II. Anti-Secretogranin II Antibody (1S984) can be used in ELISA.
AliasSN, SgII, secretogranin II, EM66, CHGC
Ig Type
Monoclonal Mouse IgG1
Clone
1S984
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Secretogranin II (rh Secretogranin II; TMPY-03968; AAH22509.1; Met1-Met617). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundKit ligand, also known as Hematopoietic growth factor KL, Mast cell growth factor, Steel factor, Stem cell factor, c-Kit ligand, Kitlg and KITL, is a single-pass type I membrane protein that belongs to the SCF family. KITL / kit ligand also belongs to the family of dimeric transmembrane growth factors. The soluble form of KIT ligand is a secreted protein. Mast cells are thought to participate in a variety of immune responses, such as parasite resistance and the allergic reaction. Mast cell development depends on stem cell factor (Kit ligand) and its receptor, c-Kit. KITL / kit ligand stimulates the proliferation of mast cells. KITL / kit ligand is able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Efficient cell surface presentation of KITL / kit ligand is essential for the migration, proliferation, and survival of melanocytes, germ cells, hemopoietic stem cells, and mastocytes. KITL / kit ligand acts synergistically with other cytokines, probably interleukins. KITL / kit ligand plays a crucial role in the development and maintenance of the melanocyte lineage in adult skin. It exerts permanent survival, proliferation and migration functions in Kit receptor-expressing melanocytes. KITL / kit ligand misexpression in some hyperpigmented lesions may open the avenue for Kitl-dependent treatment of pathological skin conditions.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human Secretogranin II Protein (TMPY-03968)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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