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Results for "

hek293 cells

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    184
    TargetMol | Inhibitors_Agonists
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    15
    TargetMol | Peptide_Products
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    7
    TargetMol | Inhibitory_Antibodies
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    TargetMol | Dye_Reagents
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    TargetMol | PROTAC
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    TargetMol | Natural_Products
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    6441
    TargetMol | Recombinant_Protein
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    TargetMol | Isotope_Products
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    8
    TargetMol | Disease_Modeling_Products
OS-3-106
T89591580000-17-4
OS-3-106 is a novel arylamide phenylpiperazines, as partial agonists at the D3R in the adenylyl cyclase inhibition assay.
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TargetMol | Inhibitor Sale
Ampicillin
D-(-)-α-Aminobenzylpenicillin, Ampicillin acid, Aminobenzylpenicillin, Amcill
T0814L69-53-4
Ampicillin (Aminobenzylpenicillin) is a semi-synthetic penicillin belonging to the β-lactam group of antibiotics. Ampicillin has bactericidal activity against a wide range of Gram-positive and Gram-negative bacteria.
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TargetMol | Inhibitor Hot
Capsaicin
Zostrix, Qutenza, 8-Methyl-N-vanillyl-trans-6-nonenamide, (E)-Capsaicin
T1062404-86-4
Capsaicin ((E)-Capsaicin) is a natural product extracted from Capsicum annuum, and is a TRPV1 agonist (EC50=0.29 μM). Capsaicin has antitumor, anti-inflammatory, antioxidant and neuroprotective activities.
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TargetMol | Inhibitor Hot
Dexamethasone
Prednisolone F, NSC 34521, MK 125, Hexadecadrol
T107650-02-2
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and IL receptor modulator with anti-inflammatory and immunosuppressive properties that induces autophagy and inhibits LPS-induced inflammatory responses in macrophages.
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TargetMol | Inhibitor Hot
VBIT-4
T132872086257-77-2
VBIT-4 is a voltage-dependent anion channel 1 (VDAC1) oligomerization inhibitor (Kd: 17 μM). VBIT-4 can be used for therapeutic purposes in apoptosis-associated disorders (such as neurodegenerative and cardiovascular diseases).
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TargetMol | Inhibitor Hot
Rapamycin
Sirolimus, NSC-2260804, AY 22989
T153753123-88-9
Rapamycin (AY 22989) is a natural product of macrolides, an mTOR inhibitor with specificity (HEK293 cells: IC50=0.1 nM). Rapamycin has immunosuppressive activity and induces autophagy.
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TargetMol | Inhibitor Hot
kainic acid
T15643487-79-6
In the CNS, Kainic acid is an effective agonist at excitatory amino acid receptor subtypes.
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7-10 days
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TargetMol | Inhibitor Hot
Defactinib
VS-6063, PF-04554878
T19961073154-85-4
Defactinib (VS-6063) is a second-generation inhibitor of FAK that inhibits FAK phosphorylation at the Tyr397 site. Defactinib has potential antitumor activity.
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TargetMol | Inhibitor Hot
Finerenone
BAY94-8862, BAY-94-8862, BAY-948862, BAY948862, BAY 94-8862, BAY 948862
T213951050477-31-0
Finerenone (BAY-948862) is a nonsteroidal antagonist of the mineralocorticoid receptor (MR) (IC50=18 nM) with selective and oral activity. Finerenone is used in the treatment of patients with chronic kidney disease with type 2 diabetes.
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TargetMol | Inhibitor Hot
Fulvestrant
ZM 182780, ZD 9238, ICI 182780
T2146129453-61-8
Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist (IC50=9.4 nM) and an agonist of GPR30. Fulvestrant has antitumor activity, inhibiting cell proliferation and inducing apoptosis and autophagy.
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TargetMol | Inhibitor Hot
Puromycin dihydrochloride
Puromycin 2HCl, CL13900 dihydrochloride
T221958-58-2
Puromycin dihydrochloride (CL13900 dihydrochloride) is a cinnamamide adenosine antibiotic and an inhibitor of protein synthesis. Puromycin dihydrochloride inhibits protein synthesis by binding to RNA and has antitumor and antitrypanosomal activity.
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TargetMol | Inhibitor Hot
Elacridar
GW120918, GW0918, GG918, GF120918
T2657143664-11-3
Elacridar (GG918) is a potent inhibitor of P-glycoprotein and BCRP.
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TargetMol | Inhibitor Hot
epacadostat
INCB 024360, IDO Inhibitor 1
T35481204669-58-8
Epacadostat (INCB 024360) is an oral, potent and selective IDO1 inhibitor with IC50 value of 71.8 nM.
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TargetMol | Inhibitor Hot
Prexasertib
LY2606368
T43101234015-52-1
Prexasertib (LY2606368) is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity.
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TargetMol | Inhibitor Hot
4-Hydroxytamoxifen
trans-4-Hydroxytamoxifen, ICI 79280, (Z)-4-hydroxy Tamoxifen
T442068047-06-3
4-Hydroxytamoxifen (ICI 79280) is the active metabolite of Tamoxifen, an estrogen receptor modulator (SERM) with selective and oral potency. 4-Hydroxytamoxifen has antitumor activity and may be used in breast cancer research.
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TargetMol | Inhibitor Hot
TREM2 agonist-2
T627502738485-98-6In house
TREM2 agonist-2 (I-192) is an orally active and potent agonist of myeloid triggered receptor 2 (TREM2) for neurodegenerative disease research.
  • Inquiry Price
6-8 weeks
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TargetMol | Inhibitor Hot
c004019
T678342417159-57-8In house
C004019 is a small molecule PROTAC capable of targeting tau for selective protein degradation from the cell, while recruiting tau and E3 ligase (Vhl) for selective enhancement of tau ubiquitination and proteollyzation. C004019 is a candidate for AD and related tau protein diseases.
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8-10 weeks
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TargetMol | Inhibitor Hot
Liraglutide
Victoza, NN2211, Liraglutidum, Liraglutida
T6876204656-20-2
Liraglutide (Liraglutida) is a synthetic analog of glucagon-like peptide-1 (GLP-1), an agonist of the GLP-1 receptor. Liraglutide can be used to treat type 2 diabetes and chronic obesity.
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TargetMol | Inhibitor Hot
6PPD-Q
6PPD-Quinone
T784742754428-18-5
6PPD-Q (6PPD-Quinone), a contaminant present in the environment and soil, is a derivative of the tire antioxidant N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD), which impairs the quality of spermatozoa in mice and induces impaired male fertility.
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TargetMol | Inhibitor Hot
Vancomycin
T86411404-90-6
Vancomycin is a glycopeptide antibiotic that exerts its antimicrobial activity by altering the permeability of cell membranes and selectively inhibiting ribonucleic acid synthesis. Vancomycin can be used for the treatment of serious infections for which all antibiotics have failed.
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TargetMol | Inhibitor Hot
Pancreatic Polypeptide, rat acetate
TP1044L
Pancreatic Polypeptide, rat acetate is an agonist of NPY receptor, with high affinity at NPYR4.
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TargetMol | Inhibitor Hot
INT-777
S-EMCA
T11662L1199796-29-6In house
INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 μM. INT-777 (S-EMCA) inhibits NLRP5-ASC inflammasome-mediated neuroinflammation via the TGR3 cAMP PKA signaling pathway after subarachnoid hemorrhage in rats.
  • Inquiry Price
8-10 weeks
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(1R,2R)-2-PCCA hydrochloride
(1R,2R)-2-PCCA(hydrochloride)
T134231609563-71-4In house
(1R,2R)-2-PCCA hydrochloride is a potent, selective, and blood-brain-barrier-crossing GPR88 receptor agonist with an EC50 value of 1140 n in striatal membranes of WT mice; it can be used to study the central nervous system.
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6-8 weeks
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Sinefungin
Antibiotic 32232RP, Adenosyl-Ornithine, A-9145
T1688658944-73-3In house
Sinefungin (Adenosyl-Ornithine) is an effective inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin is a SET7 9 inhibitor and ameliorates renal fibrosis by inhibiting H3K4 methylation.
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10-14 weeks
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