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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60220 | ROS kinases-IN-1 | ROS Kinase | |
ROS kinases-IN-1 is a ROS tyrosine kinase inhibitor with IC50 value of 1.22 μM. ROS kinases-IN-1 shows anti-tumor activity. | |||
T77762 | ROS-generating agent 1 | Apoptosis , Ferroptosis , ROS Kinase | |
Ros-generating agent 1 has anticancer activity and generates ROS by covalently modifying Sec-498 residues of TrxR. ROS-generating agent 1 reduces intracellular TrxR protein levels and promotes ROs-dependent apoptosis and... | |||
T77574 | ROS inducer 1 | ROS , Antibiotic | |
ROS inducer 1 is a small molecule compound with bactericidal activity that inhibits the production of ROS in Xanthomonas axonopodis pv. citri (Xac), Xanthomonas oryzae pv. oryzae (Xoo) and Pseudomonas syringae pv. actini... | |||
T74671 | ROS kinases-IN-2 | ROS Kinase | |
ROS kinases-IN-2 is a potent ROS kinase inhibitor with an inhibition rate of 21.53% measured at 10 μM.ROS kinases-IN-2 has potential anticancer activity and can be used to study abnormal cell growth. | |||
T19550 | ROS tracer precursor | Others | |
ROS tracer precursor, the synthesis precursor for [18F]ROStrace, serves in the production of ROStrace. This compound is instrumental in disease diagnosis. | |||
T12756 | ROS 234 dioxalate | Histamine Receptor | |
ROS 234 dioxalate is a potent antagonist of H3(pKB of 9.46 for Guinea-pig ileum H3-receptor) | |||
T60340 | ROS 234 | ||
ROS 234 is a highly effective H3 antagonist, demonstrating a strong binding affinity (pK B) of 9.46 for the Guinea-pig ileum H3 receptor and a pKi of 8.90 for the Rat cerebral cortex H3 receptor. Additionally, it exhibit... | |||
T78887 | ROS-IN-2 | Reactive Oxygen Species | |
ROS-IN-2 (compound 85), a seco-lupane triterpenoid derivative, inhibits reactive oxygen species (ROS) production and shields mitochondria from oxidative damage by curtailing the generation of oxidative stressors. It has ... | |||
T79517 | ROS inducer 2 | Reactive Oxygen Species | |
Compound I16 (ROS inducer 2) is a potent inducer of Reactive Oxygen Species (ROS) with an effective concentration (EC 50) of 3.43 μg/mL demonstrated in vitro. It exhibits exceptional bioactivity in vivo against Xanthomon... | |||
T79518 | ROS inducer 3 | Reactive Oxygen Species | |
Compound I6 (ROS inducer 3) is a potent ROS inducer with robust in vitro bioactivity, demonstrated by an EC50 of 2.86 μg/mL. It exhibits significant protective activity against Pseudomonas syringae pv. actinidiae, and as... | |||
T74225 | ROS-ERS inducer 1 | ||
ROS-ERS inducer 1, a type II immunogenic cell death (ICD) inducer, is a Pt(II)-N-heterocyclic carbene (Pt(II)-NHC) complex derived from 4,5-diarylimidazole. It induces endoplasmic reticulum stress (ERS) along with reacti... | |||
TMS1743 | Salvigenin | MAO , Autophagy , ROS Kinase | |
Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects. | |||
TD0102 | 1,3-Diphenylisobenzofuran | DPBF | Others |
1,3-Diphenylisobenzofuran (DPBF) is a fluorescent probe. It possesses a highly specific reactivity towards singlet oxygen forming an endoperoxide which decomposes to give 1,2-dibenzoylbenzene. 1,3-Diphenylisobenzofuran c... | |||
T21482 | Uniconazole | P450 , ROS Kinase | |
Uniconazole is a plant growth regulator that inhibit cytochrome P450 707As (Ki=68 nM). CYP707As is a major ABA catabolic enzyme that catabolize Abscisic acid, accordingly suppress gibberellin and sterol biosynthesis. | |||
T7831 | Nitecapone | Others , Transferase | |
Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver) | |||
TQ0089 | Juglanin | Apoptosis , JNK , Autophagy | |
Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells. | |||
T10668 | Camalexin | Reactive Oxygen Species , ROS , Antibacterial , Antifungal | |
Camalexin is a phytoalexin isolated from Camelina sativa. It has antifungal, antibacterial, antiproliferative, and anticancer activities. Camalexin can induce ROS production. | |||
TN2097 | Pomolic acid | Apoptosis , Caspase , HIV Protease , AMPK | |
Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-mediated intrinsic and death receptor-induced extrinsic pathways. | |||
T7538 | Tetraethylammonium chloride | Potassium Channel | |
Tetraethylammonium chloride is a quaternary ammonium compound. It is a non-selective potassium channel blocker. It is a good substrate for organic cation transporter proteins and has antitumor properties. | |||
T36735 | 3,5-Di-tert-butylphenol | Reactive Oxygen Species , Antifungal | |
3,5-Di-tert-butylphenol induces accumulation of reactive oxygen species. 3,5-Di-tert-butylphenol exhibits anti-biofilm and antifungal activities. |