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Anti-Prostatic acid phosphatase Antibody (6N840) is a Mouse antibody targeting Prostatic acid phosphatase. Anti-Prostatic acid phosphatase Antibody (6N840) can be used in IHC-P,IF,IHC-Fr.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days |
| Description | Anti-Prostatic acid phosphatase Antibody (6N840) is a Mouse antibody targeting Prostatic acid phosphatase. Anti-Prostatic acid phosphatase Antibody (6N840) can be used in IHC-P,IF,IHC-Fr. |
| Ig Type | IgG2b, Kappa |
| Clone | 6N840 |
| Reactivity | Human (predicted:Mouse,Rat) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IF: 1:100-500; IHC-Fr: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Isoform 1: Secreted. Isoform 2: Cell membrane. Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling. |
| Tissue Specificity | Highly expressed in the prostate, restricted to glandular and ductal epithelial cells. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | PBS containing 50% Glycerol, 0.5% BSA and 0.02% Proclin300. |
| Concentration | 1mg/ml |
| Research Background | Prostatic Acid Phosphatase is Belongs to the histidine acid phosphatase family.Cellular localization;Secreted and Lysosome membrane. Predominantly localized in the plasma membrane but also detected in intracellular vesicles. |
| Immunogen | KLH conjugated synthetic peptide: human Prostatic Acid Phosphatase |
| Antigen Species | Human |
| Gene Name | ACP3 |
| Gene ID | |
| Protein Name | Prostatic acid phosphatase |
| Uniprot ID | |
| Function | A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. |
| Molecular Weight | Theoretical: 41 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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