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(E/Z)-Squalene

Name: (E/Z)-Squalene
Brand: TargetMol
SKU: T75636
Price: 50 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T75636Cas No. 7683-64-9

Alias (E/Z)-Super Squalene, (E/Z)-AddaVax

(E/Z)-Squalene ((E/Z)-AddaVax) regulates intracellular reactive oxidant species (ROS) production, induces apoptosis and necrosis in a concentration- and time-dependent manner, accumulates in the liver, and lowers hepatic cholesterol and triglycerides.

(E/Z)-Squalene

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Purity: 98.15%

Catalog No. T75636Alias (E/Z)-Super Squalene, (E/Z)-AddaVaxCas No. 7683-64-9

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$50	-	In Stock
25 mg	$55	-	In Stock
50 mg	$81	-	In Stock
100 mg	$122	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.15%

Appearance:Liquid

Color:Transparent

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	(E/Z)-Squalene ((E/Z)-AddaVax) regulates intracellular reactive oxidant species (ROS) production, induces apoptosis and necrosis in a concentration- and time-dependent manner, accumulates in the liver, and lowers hepatic cholesterol and triglycerides.
In vitro	(E/Z)-Squalene (0-50 μM) in human breast epithelial cells (MCF10A) decreases intracellular ROS levels, thereby preventing H2O2-induced oxidative damage and protecting against DNA oxidative damage.[1]
Synonyms	(E/Z)-Super Squalene, (E/Z)-AddaVax

Chemical Properties

Molecular Weight	410.72
Formula	C₃₀H₅₀
Cas No.	7683-64-9
Smiles	C(CC(=CCCC=C(CCC=C(CCC=C(C)C)C)C)C)C=C(CCC=C(C)C)C

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (121.74 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4347 mL	12.1737 mL	24.3475 mL	121.7374 mL
5 mM	0.4869 mL	2.4347 mL	4.8695 mL	24.3475 mL
10 mM	0.2435 mL	1.2174 mL	2.4347 mL	12.1737 mL
20 mM	0.1217 mL	0.6087 mL	1.2174 mL	6.0869 mL
50 mM	0.0487 mL	0.2435 mL	0.4869 mL	2.4347 mL
100 mM	0.0243 mL	0.1217 mL	0.2435 mL	1.2174 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc