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Anti-BCMA/TNFRSF17 Antibody (1M731)
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Catalog No. TMAY-01036
Alias tumor necrosis factor receptor superfamily member 17, TNFRSF13A, CD269, BCMA, BCM
Anti-BCMA/TNFRSF17 Antibody (1M731) is a Rabbit antibody targeting BCMA/TNFRSF17. Anti-BCMA/TNFRSF17 Antibody (1M731) can be used in ELISA.
Anti-BCMA/TNFRSF17 Antibody (1M731)
Anti-BCMA/TNFRSF17 Antibody (1M731)
😃Good
Catalog No. TMAY-01036Alias tumor necrosis factor receptor superfamily member 17, TNFRSF13A, CD269, BCMA, BCM
Anti-BCMA/TNFRSF17 Antibody (1M731) is a Rabbit antibody targeting BCMA/TNFRSF17. Anti-BCMA/TNFRSF17 Antibody (1M731) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $92 | 7-10 days | |
| 100 μL | $270 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | tumor necrosis factor receptor superfamily member 17, TNFRSF13A, CD269, BCMA, BCM |
| Ig Type | Rabbit IgG |
| Clone | 1M731 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human BCMA / TNFRSF17 (rh BCMA / TNFRSF17; TMPY-04493; NP_001183.2; Met1-Ala54). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13BBAFF), and to lead to NF-kappaB and MAPK8/JNK activation. TNFRSF17/BCMA/CD269 also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. TNFRSF17/BCMA/CD269 is a receptor for TALL-1 and BCMA activates NF-kappaB through a TRAF5-, TRAF6-, NIK-, and IKK-dependent pathway. The identification of TNFRSF17 as a NF-kappaB-activating receptor for TALL-1 suggests molecular targets for drug development against certain immunodeficient or autoimmune diseases. TNFRSF17/BCMA is a target of donor B-cell immunity in patients with myeloma who respond to DLI. Antibody responses to cell-surface BCMA may contribute directly to tumor rejection in vivo. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human BCMA / TNFRSF17 Protein (TMPY-04493) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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