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2-benzylsulfanyl-6-methoxy-4-methylquinazoline
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Catalog No. T72072Cas No. 500272-00-4
2-benzylsulfanyl-6-methoxy-4-methylquinazoline can be used as a TRPML modulator for the treatment of diseases associated with TRPML activity, such as lysosomal storage disease, muscular dystrophy, oxidative stress or reactive oxygen species (ROS)-related diseases and ageing.
2-benzylsulfanyl-6-methoxy-4-methylquinazoline
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Purity: 99.5%
Catalog No. T72072Cas No. 500272-00-4
2-benzylsulfanyl-6-methoxy-4-methylquinazoline can be used as a TRPML modulator for the treatment of diseases associated with TRPML activity, such as lysosomal storage disease, muscular dystrophy, oxidative stress or reactive oxygen species (ROS)-related diseases and ageing.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $195 | - | In Stock | |
| 5 mg | $440 | - | In Stock | |
| 10 mg | $648 | - | In Stock | |
| 25 mg | $987 | - | In Stock | |
| 50 mg | $1,390 | - | In Stock | |
| 100 mg | $1,870 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $428 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.5%
Appearance:Solid
Color:Yellow
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Product Introduction
2-benzylsulfanyl-6-methoxy-4-methylquinazoline AI Summary
2-benzylsulfanyl-6-methoxy-4-methylquinazoline exhibits a variety of bioactivities based on the assays conducted. It has shown potency as an activator or inhibitor in various pathways, including modulating miRNAs, activating specific promoters, inhibiting enzyme activities such as histone lysine methyltransferase and aldehyde dehydrogenase, inducing genotoxicity in cells, targeting specific protein-protein interactions, and inhibiting viral entry into cells. These results suggest that 2-benzylsulfanyl-6-methoxy-4-methylquinazoline has potential bioactive properties in regulating various cellular processes and pathways..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | 2-benzylsulfanyl-6-methoxy-4-methylquinazoline can be used as a TRPML modulator for the treatment of diseases associated with TRPML activity, such as lysosomal storage disease, muscular dystrophy, oxidative stress or reactive oxygen species (ROS)-related diseases and ageing. |
| Molecular Weight | 296.39 |
| Formula | C17H16N2OS |
| Cas No. | 500272-00-4 |
| Smiles | COC1=CC2=C(C=C1)N=C(SCC1=CC=CC=C1)N=C2C |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 12 mg/mL (40.49 mM), Sonication is recommended.  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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