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Anti-BCMA/TNFRSF17 Antibody (6D874)

(Synonyms: tumor necrosis factor receptor superfamily member 17, TNFRSF13A, CD269, BCMA, BCM) Copy Product Info
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Synonyms: tumor necrosis factor receptor superfamily member 17, TNFRSF13A, CD269, BCMA, BCM

Catalog No. TMAH-01189 Copy Product Info
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Anti-BCMA/TNFRSF17 Antibody (6D874) is a Mouse antibody targeting BCMA/TNFRSF17. Anti-BCMA/TNFRSF17 Antibody (6D874) can be used in ELISA,IHC,WB.

Anti-BCMA/TNFRSF17 Antibody
(6D874)

Pack SizePriceUSA StockGlobal StockQuantity
50 µL$2077-10 days7-10 days
100 µL$3497-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-BCMA/TNFRSF17 Antibody (6D874) is a Mouse antibody targeting BCMA/TNFRSF17. Anti-BCMA/TNFRSF17 Antibody (6D874) can be used in ELISA,IHC,WB.
Synonymstumor necrosis factor receptor superfamily member 17, TNFRSF13A, CD269, BCMA, BCM
Ig Type
IgG2b
Clone
6D874
Reactivity
Human
Verified Activity
1. Western Blot
-Positive WB detected in: 1-2 lanes: 293F whole cell lysate transfected with BCMA; 3-4 lane: Recombinant proteins with BCMA
-All lanes: TNFRSF17 antibody at 1:1000
-Secondary: Goat polyclonal to mouse IgG at 1/50000 dilution
-Predicted band size: 40, 15 KDa
-Observed band size: 40, 15 KDa
-Exposure time:10min
2. IHC image of TMAH-01189 diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at 37°C Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-Mouse IgG labeled by HRP and visualized using 0.05% DAB.
3. IHC image of TMAH-01189 diluted at 1:100 and staining in paraffin-embedded human colon tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at 37°C Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-Mouse IgG labeled by HRP and visualized using 0.05% DAB.
4. IHC image of TMAH-01189 diluted at 1:100 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at 37°C Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-Mouse IgG labeled by HRP and visualized using 0.05% DAB.
Application
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationCell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. Note=Perinuclear Golgi-like structures.
Tissue SpecificityExpressed in mature B-cells, but not in T-cells or monocytes.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
FormulationPreservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
Purity>95%
Research BackgroundReceptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human TNFRSF17 Protein (1-54AA)
Antigen Species
Human
Gene Name
TNFRSF17
Gene ID
Uniprot ID
Biology Area
Immunology
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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