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Aminochalcone 4AAF
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Catalog No. T211786Cas No. 38239-51-9
Aminochalcone 4AAF is a neuroprotective agent that exhibits anxiolytic effects through its interaction with GABAA and 5-HT receptors. It shows high selectivity for 5-HT3A and 5-HT2C receptors and modulates allosteric behavior at the 5-HT2A receptor. Aminochalcone 4AAF is known for its hypoglycemic properties and reduces reactive oxygen species (ROS) levels in the liver. It also delays the tonic phase of seizures. This compound is useful in research on anxiety, hyperglycemia, and epilepsy.
Aminochalcone 4AAF
😃Good
Catalog No. T211786Cas No. 38239-51-9
Aminochalcone 4AAF is a neuroprotective agent that exhibits anxiolytic effects through its interaction with GABAA and 5-HT receptors. It shows high selectivity for 5-HT3A and 5-HT2C receptors and modulates allosteric behavior at the 5-HT2A receptor. Aminochalcone 4AAF is known for its hypoglycemic properties and reduces reactive oxygen species (ROS) levels in the liver. It also delays the tonic phase of seizures. This compound is useful in research on anxiety, hyperglycemia, and epilepsy.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | Aminochalcone 4AAF is a neuroprotective agent that exhibits anxiolytic effects through its interaction with GABAA and 5-HT receptors. It shows high selectivity for 5-HT3A and 5-HT2C receptors and modulates allosteric behavior at the 5-HT2A receptor. Aminochalcone 4AAF is known for its hypoglycemic properties and reduces reactive oxygen species (ROS) levels in the liver. It also delays the tonic phase of seizures. This compound is useful in research on anxiety, hyperglycemia, and epilepsy. |
| In vivo | Aminochalcone 4AAF (20 uL of 0.1-10 mg/mL, oral, single administration) exhibits both anxiolytic and hypoglycemic effects, effectively reversing anxiety and elevated blood glucose levels induced by sucrose in adult zebrafish, as well as delaying the tonic phase of seizures. |
| Molecular Weight | 223.27 |
| Formula | C15H13NO |
| Cas No. | 38239-51-9 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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