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Anti-VEGFR3/FLT4 Antibody (2H101) is a Mouse antibody targeting VEGFR3/FLT4. Anti-VEGFR3/FLT4 Antibody (2H101) can be used in ELISA(Det).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $69 | 7-10 days | |
100 μL | $199 | 7-10 days |
Description | Anti-VEGFR3/FLT4 Antibody (2H101) is a Mouse antibody targeting VEGFR3/FLT4. Anti-VEGFR3/FLT4 Antibody (2H101) can be used in ELISA(Det). |
Alias | VEGFR-3, VEGFR3, VEGF Receptor 3, PCL, LMPH1A, fms related tyrosine kinase 4, FLT-41, FLT41, FLT-4 |
Ig Type | Monoclonal Mouse IgG2a |
Clone | 2H101 |
Reactivity | Human |
Application | ELISA(Det) |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human VEGFR3 / FLT-4 (rh VEGFR3 / FLT-4 ; TMPY-00949; NP_002011.2; Met1-Ile776). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR3 signaling pathway may provide a target for antilymphangiogenic therapy in prostate cancer, breast cancer, gastric cancer, lung cancer, non-small cell lung cancer (NSCLC), and so on.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
Conjucates | Unconjugated |
Others Formats | HRP |
Antibody Types Available | 2 |
Immunogen | Recombinant Human VEGFR3 / FLT-4 Protein (TMPY-00949) |
Antigen Species | Human |
Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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