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MK-2894

Name: MK-2894
Brand: TargetMol
SKU: T12061
Price: 55 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T12061Cas No. 1006036-87-8

Alias MK2894, MK 2894

MK-2894 is a prostaglandin receptor 4 antagonist.MK-2894 has anti-inflammatory activity and may be used in the study of inflammation.

MK-2894

🥰Excellent

Purity: 99.22%

Catalog No. T12061Alias MK2894, MK 2894Cas No. 1006036-87-8

MK-2894 is a prostaglandin receptor 4 antagonist.MK-2894 has anti-inflammatory activity and may be used in the study of inflammation.

Pack Size	Price	Availability
1 mg	$55	In Stock
5 mg	$129	In Stock
10 mg	$228	In Stock
25 mg	$553	In Stock
50 mg	$977	In Stock
100 mg	$1,290	In Stock
500 mg	$2,630	In Stock
1 mL x 10 mM (in DMSO)	$137	In Stock

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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.22%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	MK-2894 is a prostaglandin receptor 4 antagonist.MK-2894 has anti-inflammatory activity and may be used in the study of inflammation.
Targets&IC50	EP4:2.5 nM, EP4:0.56 nM (Ki)
Synonyms	MK2894, MK 2894

Chemical Properties

Molecular Weight	473.51
Formula	C₂₅H₂₂F₃NO₃S
Cas No.	1006036-87-8
Smiles	Cc1sc(C)c(C(=O)NC2(CC2)c2ccc(cc2)C(O)=O)c1Cc1ccc(cc1)C(F)(F)F
Relative Density.	1.39 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (105.59 mM), Sonication is recommended.

H2O: < 1 mg/mL (Insoluble)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1119 mL	10.5594 mL	21.1189 mL	105.5944 mL
5 mM	0.4224 mL	2.1119 mL	4.2238 mL	21.1189 mL
10 mM	0.2112 mL	1.0559 mL	2.1119 mL	10.5594 mL
20 mM	0.1056 mL	0.5280 mL	1.0559 mL	5.2797 mL
50 mM	0.0422 mL	0.2112 mL	0.4224 mL	2.1119 mL
100 mM	0.0211 mL	0.1056 mL	0.2112 mL	1.0559 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc