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Anti-HGFR/c-Met Antibody (4V580)

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Catalog No. TMAY-01071
Alias MET proto-oncogene, receptor tyrosine kinase

Anti-HGFR/c-Met Antibody (4V580) is a Rabbit antibody targeting HGFR/c-Met. Anti-HGFR/c-Met Antibody (4V580) can be used in FCM.

Anti-HGFR/c-Met Antibody (4V580)

Anti-HGFR/c-Met Antibody (4V580)

😃Good
Catalog No. TMAY-01071Alias MET proto-oncogene, receptor tyrosine kinase
Anti-HGFR/c-Met Antibody (4V580) is a Rabbit antibody targeting HGFR/c-Met. Anti-HGFR/c-Met Antibody (4V580) can be used in FCM.
Pack SizePriceAvailabilityQuantity
20 μL$92 7-10 days
100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Anti-HGFR/c-Met Antibody (4V580) is a Rabbit antibody targeting HGFR/c-Met. Anti-HGFR/c-Met Antibody (4V580) can be used in FCM.
AliasMET proto-oncogene, receptor tyrosine kinase
Ig Type
Monoclonal Rabbit IgG
Clone
4V580
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human C-Met(HGFR) expression on HepG2 cells. Cells were stained with purified anti-Human C-Met(HGFR), then a FITC-conjugated second step antibody. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
FCM
Recommended Dose
FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human c-Met / HGFR (rh c-Met / HGFR; TMPY-01296; NP_000236.2; Met1-Thr932).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundHepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR protein is produced as a single-chain precursor, and HGF is the only known ligand. Normal HGF/HGFR signaling is essential for embryonic development, tissue repair, or wound healing, whereas aberrantly active HGFR has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes. HGFR protein is a multifaceted regulator of growth, motility, and invasion, and is normally expressed by cells of epithelial origin. Preclinical studies suggest that targeting aberrant HGFR signaling could be an attractive therapy in cancer.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
APC/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Human c-Met / HGFR protein (TMPY-01296)
Antigen Species
Human
Biology Area
Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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