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Anti-HGFR/c-Met Antibody (4Y373) (Synonyms: MET proto-oncogene, receptor tyrosine kinase)
Catalog No. TMAY-01067 Copy Product Info
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Anti-HGFR/c-Met Antibody (4Y373) is a Mouse antibody targeting HGFR/c-Met. Anti-HGFR/c-Met Antibody (4Y373) can be used in WB.
Anti-HGFR/c-Met Antibody (4Y373)
Copy Product Info🥰Excellent
Catalog No. TMAY-01067
Synonyms MET proto-oncogene, receptor tyrosine kinase
Anti-HGFR/c-Met Antibody (4Y373) is a Mouse antibody targeting HGFR/c-Met. Anti-HGFR/c-Met Antibody (4Y373) can be used in WB.
Anti-HGFR/c-Met Antibody
(4Y373)
(4Y373)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $198 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-HGFR/c-Met Antibody (4Y373) is a Mouse antibody targeting HGFR/c-Met. Anti-HGFR/c-Met Antibody (4Y373) can be used in WB. |
| Synonyms | MET proto-oncogene, receptor tyrosine kinase |
| Ig Type | Mouse IgG1 |
| Clone | 4Y373 |
| Reactivity | Human |
| Specificity | Human c-MET/HGFR |
| Verified Activity | 1. Anti-HGFR mouse monoclonal antibody at 1:500 dilution. -Lane A: Hela Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Mouse IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:156 kDa. 2. Anti-c-MET mouse monoclonal antibody at 1:500 dilution. -Lane A: Hela Whole Cell Lysate. -Lane B: c-MET konckout Hela Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Mouse IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:156 kDa(Validation Experiment) |
| Application | |
| Recommended Dose | WB: 1:500-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human c-MET (rh c-MET; TMPY-01296; NP_000236.2; Met1-Thr932). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR protein is produced as a single-chain precursor, and HGF is the only known ligand. Normal HGF/HGFR signaling is essential for embryonic development, tissue repair, or wound healing, whereas aberrantly active HGFR has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes. HGFR protein is a multifaceted regulator of growth, motility, and invasion, and is normally expressed by cells of epithelial origin. Preclinical studies suggest that targeting aberrant HGFR signaling could be an attractive therapy in cancer.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human c-MET Protein (TMPY-01296) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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