Goodyeroside A is a natural glycoside that inhibits liver damage caused by substances such as carbon tetrachloride, and is also effective in suppressing inflammation by inhibiting the NF-κB signalling pathway.

Goodyeroside A exhibits anti-inflammatory activity in vitro by suppressing LPS-induced NO production, iNOS expression, and proinflammatory cytokine release (TNF-α, IL-6) in RAW264.7 macrophages (0.1-10 μM, 24 h), without showing cytotoxicity[1].

Goodyeroside A (25 and 50 mg/kg, oral) significantly reduces ear swelling and inflammatory cell infiltration in a mouse ear edema model induced by croton oil, supporting its anti-inflammatory effect[1].