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Anti-GITR/TNFRSF18 Antibody (8R877) (Synonyms: tumor necrosis factor receptor superfamily, member 18, GITR-D, ...)

Name: Anti-GITR/TNFRSF18 Antibody (8R877)
Brand: TargetMol
SKU: TMAY-02614
Rating: 4.5 (1 reviews)

Catalog No. TMAY-02614 Copy Product Info

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Anti-GITR/TNFRSF18 Antibody (8R877) is a Mouse antibody targeting GITR/TNFRSF18. Anti-GITR/TNFRSF18 Antibody (8R877) can be used in ELISA.

Anti-GITR/TNFRSF18 Antibody (8R877)

Copy Product Info

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Catalog No. TMAY-02614

Synonyms tumor necrosis factor receptor superfamily, member 18, GITR-D, GITR, CD357, AITR

Anti-GITR/TNFRSF18 Antibody (8R877) is a Mouse antibody targeting GITR/TNFRSF18. Anti-GITR/TNFRSF18 Antibody (8R877) can be used in ELISA.

Anti-GITR/TNFRSF18 Antibody
(8R877)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 μL	$199	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-GITR/TNFRSF18 Antibody (8R877) is a Mouse antibody targeting GITR/TNFRSF18. Anti-GITR/TNFRSF18 Antibody (8R877) can be used in ELISA.
Synonyms	tumor necrosis factor receptor superfamily, member 18, GITR-D, GITR, CD357, AITR
Ig Type	Mouse IgG2a
Clone	8R877
Reactivity	Human
Specificity	Human GITR/TNFRSF18/AITR
Application	ELISA
Recommended Dose	ELISA: 1:1000-1:2000
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GITR/TNFRSF18/CD357 (rh GITR/TNFRSF18/CD357; TMPY-00072; NP_683700.1; Met1-Glu161). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases. It also mediates NF-kappa-B activation via the TRAF2/NIK pathway.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Human GITR/TNFRSF18/CD357 Protein (TMPY-00072)
Antigen Species	Human
Biology Area	Cancer Drug Targets

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

CD-357CD 357

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