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Anti-GITR/TNFRSF18 Antibody (8R877)
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Catalog No. TMAY-02614
Alias tumor necrosis factor receptor superfamily, member 18, GITR-D, GITR, CD357, AITR
Anti-GITR/TNFRSF18 Antibody (8R877) is a Mouse antibody targeting GITR/TNFRSF18. Anti-GITR/TNFRSF18 Antibody (8R877) can be used in ELISA.
Anti-GITR/TNFRSF18 Antibody (8R877)
Anti-GITR/TNFRSF18 Antibody (8R877)
😃Good
Catalog No. TMAY-02614Alias tumor necrosis factor receptor superfamily, member 18, GITR-D, GITR, CD357, AITR
Anti-GITR/TNFRSF18 Antibody (8R877) is a Mouse antibody targeting GITR/TNFRSF18. Anti-GITR/TNFRSF18 Antibody (8R877) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Chemical Properties
| Description | Anti-GITR/TNFRSF18 Antibody (8R877) is a Mouse antibody targeting GITR/TNFRSF18. Anti-GITR/TNFRSF18 Antibody (8R877) can be used in ELISA. |
| Alias | tumor necrosis factor receptor superfamily, member 18, GITR-D, GITR, CD357, AITR |
| Ig Type | Monoclonal Mouse IgG2a |
| Clone | 8R877 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GITR/TNFRSF18/CD357 (rh GITR/TNFRSF18/CD357; TMPY-00072; NP_683700.1; Met1-Glu161). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases. It also mediates NF-kappa-B activation via the TRAF2/NIK pathway.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human GITR/TNFRSF18/CD357 Protein (TMPY-00072) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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