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BS3 Crosslinker

Name: BS3 Crosslinker
Brand: TargetMol
SKU: T14833
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T14833Cas No. 82436-77-9

Alias BSSIS, Bis(sulfosuccinimidyl)suberate

BS3 Crosslinker (Bis(sulfosuccinimidyl)suberate) is an ADC linker that makes amino groups react with each other and can be used to synthesize antibody-coupled reactive molecules.

BS3 Crosslinker

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Purity: 99.84%

Catalog No. T14833Alias BSSIS, Bis(sulfosuccinimidyl)suberateCas No. 82436-77-9

BS3 Crosslinker (Bis(sulfosuccinimidyl)suberate) is an ADC linker that makes amino groups react with each other and can be used to synthesize antibody-coupled reactive molecules.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$30	-	In Stock
10 mg	$48	-	In Stock
25 mg	$98	-	In Stock
50 mg	$153	-	In Stock
100 mg	$223	-	In Stock
200 mg	$323	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.84%

Appearance:Solid

Color:White

Resource Download

COA HNMR MS HPLC

Product Introduction

Bioactivity

Description	BS3 Crosslinker (Bis(sulfosuccinimidyl)suberate) is an ADC linker that makes amino groups react with each other and can be used to synthesize antibody-coupled reactive molecules.
Synonyms	BSSIS, Bis(sulfosuccinimidyl)suberate

Chemical Properties

Molecular Weight	528.47
Formula	C₁₆H₂₀N₂O₁₄S₂
Cas No.	82436-77-9
Smiles	O=C(ON1C(=O)CC(C1=O)S(=O)(=O)O)CCCCCCC(=O)ON2C(=O)CC(C2=O)S(=O)(=O)O
Relative Density.	1.78 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 80 mg/mL (151.38 mM), Sonication is recommended.

DMSO: 255 mg/mL (482.53 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8923 mL	9.4613 mL	18.9226 mL	94.6128 mL
5 mM	0.3785 mL	1.8923 mL	3.7845 mL	18.9226 mL
10 mM	0.1892 mL	0.9461 mL	1.8923 mL	9.4613 mL
20 mM	0.0946 mL	0.4731 mL	0.9461 mL	4.7306 mL
50 mM	0.0378 mL	0.1892 mL	0.3785 mL	1.8923 mL
100 mM	0.0189 mL	0.0946 mL	0.1892 mL	0.9461 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc