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Atrosab
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Catalog No. T80561 Copy Product Info
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Atrosab is a humanized IgG1 antibody targeting TNFR1, inhibiting TNF-mediated apoptosis, and can be used to study inflammatory and neurodegenerative diseases.
Cas No. 1365659-05-7
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $247 | In Stock | In Stock | |
| 5 mg | $619 | In Stock | In Stock | |
| 10 mg | $987 | In Stock | In Stock | |
| 25 mg | $1,470 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95.22% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
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| Description | Atrosab is a humanized IgG1 antibody targeting TNFR1, inhibiting TNF-mediated apoptosis, and can be used to study inflammatory and neurodegenerative diseases. |
| In vitro | Binding of Atrosab to MEF-TNFR1-Fas was comparable to that of H398 as shown by a titration of antibody concentration. The EC50 values were approximately 0.1 nM for both Atrosab and H398. [1] |
| Expression System | CHO |
| Endotoxin | <1.0 EU/mg |
| Reactivity | Human |
| Verified Activity | Immobilized Human TNFR1/CD120a/TNFRSF1A Protein (His) (TMPY-01459) at 10 μg/mL (100 μL/well) can bind Atrosab. The EC50 is 2.62 ng/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TNFR1 |
| Molecular Weight | 146.12 kDa |
| Cas No. | 1365659-05-7 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Atrosab chemical structure | Atrosab in vitro | Atrosab molecular weight
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