Xanthine oxidase (XO) is an enzyme involved in purine catabolism and conversion to uric acid, generating reactive oxygen species, used in the study of cardiovascular diseases.

In Xanthine oxidase (20 mU/ml,72h), 90% growth inhibition of malaria parasite was observed in human O + red blood cells, with IC50 = 0.2mU /ml. [1]
Administration of Xanthine oxidase (0.02 U/ml) for 1 or 6 h reduced the viability of 8 div cells and induced morphological changes, such as contraction of cell bodies and neurites. [2]

The elevated level of Xanthine oxidase was positively correlated with chronic liver disease (cirrhosis, chronic hepatitis and cholestatic disease), and had nothing to do with liver injury indicators. [3]