Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

TUG-2181

😃Good
Catalog No. T206822Cas No. 2653994-24-0

TUG-2181 is an antagonist of GPR84, with an IC50 value of 34 nM. It inhibits reactive oxygen species (ROS) production and IL-8 secretion induced by GPR84 agonists in human neutrophils. TUG-2181 is applicable for research in inflammation and fibrosis.

TUG-2181

TUG-2181

😃Good
Catalog No. T206822Cas No. 2653994-24-0
TUG-2181 is an antagonist of GPR84, with an IC50 value of 34 nM. It inhibits reactive oxygen species (ROS) production and IL-8 secretion induced by GPR84 agonists in human neutrophils. TUG-2181 is applicable for research in inflammation and fibrosis.
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Resource Download

Product Introduction

Bioactivity
Description
TUG-2181 is an antagonist of GPR84, with an IC50 value of 34 nM. It inhibits reactive oxygen species (ROS) production and IL-8 secretion induced by GPR84 agonists in human neutrophils. TUG-2181 is applicable for research in inflammation and fibrosis.
Chemical Properties
Molecular Weight357.443
FormulaC21H27NO4
Cas No.2653994-24-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy TUG-2181 | purchase TUG-2181 | TUG-2181 cost | order TUG-2181 | TUG-2181 chemical structure | TUG-2181 formula | TUG-2181 molecular weight